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The Patterns of Sleep Disorders and Circadian Rhythm Disruptions in Children and Adolescents with Fetal Alcohol Spectrum Disorders

Background: Sleep disorders have been poorly described in children and adolescents diagnosed with FASD. The objective of this study is to describe the sleep and circadian rhythm characteristics of children with FASD using overnight polysomnography, sleep questionnaires, and the Dim Light Melatonin Onset (DLMO) test. To our knowledge, no comprehensive studies of this nature have been conducted. Methods: Children ages 6-18 years diagnosed with Fetal Alcohol Spectrum Disorder (FASD) were recruited from various FASD clinics to the Youthdale Child and Adolescent Sleep Centre in Toronto. After medical consultation, each participant had one night of overnight polysomnography, as well as an additional night of DLMO. Participants completed various sleep and FASD questionnaires. Results: Significant differences were found when comparing the sleep architecture of FASD participants to normative data. There was a high prevalence of sleep disorders in this sample. Most of the melatonin profiles of the FASD participants were found to be abnormal.

Identiferoai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:OTU.1807/30610
Date07 December 2011
CreatorsGoril, Shery
ContributorsShapiro, Colin M.
Source SetsLibrary and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada
Languageen_ca
Detected LanguageEnglish
TypeThesis

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