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Investigation of Rotational Deviations on Single Fiducial Tumor Tracking with Simulated Respiratory Motion using Synchrony® Respiratory Motion Tracking for Cyberknife® Treatment

It is hypothesized that the uncertainty of the Synchrony® model from the rotation of a
geometrically asymmetrical single fiducial shall be non-zero during the motion tracking.
To validate this hypothesis, the uncertainty was measured for a Synchrony® model built
for a respiratory motion phantom oriented at different yaw angles on a Cyberknife®
treatment table.
A Mini-ball Cube with three cylindrical GoldMark™ (1mmx5mm Au) numbered
fiducials was placed inside a respiratory phantom and used for all tests. The fiducial with
the least artifact interference was selected for the motion tracking. A 2cm periodic,
longitudinal, linear motion of the Mini-ball cube was executed and tested for yaw
rotational angles, 0° – 90°. The test was repeated over 3 nonconsecutive days. The
uncertainty increased with the yaw angle with the most noticeable changes seen
between20° and 60° yaw, where uncertainty increased from 23.5% to 57.9%. A similar test was performed using a spherical Gold Anchor™ fiducial. The uncertainties found
when using the Gold Anchor™ were statistically lower than those found when using the
GoldMark™ fiducial for all angles of rotation.
For the first time, it is found that Synchrony® model uncertainty depends on fiducial
geometry. In addition, this research has shown that tracking target rotation using a single
fiducial can be accomplished with the Synchrony® model uncertainty as it is displayed on
the treatment console.
The results of this research could lead to decreased acute toxicity effects related to
multiple fiducials. / Includes bibliography. / Thesis (M.S.)--Florida Atlantic University, 2018. / FAU Electronic Theses and Dissertations Collection

Identiferoai:union.ndltd.org:fau.edu/oai:fau.digital.flvc.org:fau_40789
ContributorsChrist, Zachary A. (author), Shang, Charles (Thesis advisor), Leventouri, Theodora (Thesis advisor), Florida Atlantic University (Degree grantor), Charles E. Schmidt College of Science, Department of Physics
PublisherFlorida Atlantic University
Source SetsFlorida Atlantic University
LanguageEnglish
Detected LanguageEnglish
TypeElectronic Thesis or Dissertation, Text
Format45 p., application/pdf
RightsCopyright © is held by the author, with permission granted to Florida Atlantic University to digitize, archive and distribute this item for non-profit research and educational purposes. Any reuse of this item in excess of fair use or other copyright exemptions requires permission of the copyright holder., http://rightsstatements.org/vocab/InC/1.0/

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