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Particle Focusing in Microchannels

The ability to control the motion of particles and cells in microchannels has been a center of fascination since the advent of microfluidics. Entire fields have been created in order to accomplish separation, volume reduction and overall positioning of particles and cells within microfluidic devices in the fastest and most accurate manner possible. While most of these technologies rely on low Reynolds number operation, one technique entitled inertial focusing takes advantage of the inertia of the surrounding fluid and the interaction between a particle and the channel itself which cause the lateral migration of particles across streamlines to equilibrium positions within a flow. The major advantage of inertial microfluidics in biomedical and microfluidic applications is that it is inherently high throughput being dependent on inertia whereas most microfluidic concepts are dependent on low Reynolds number operation. / Engineering and Applied Sciences

Identiferoai:union.ndltd.org:harvard.edu/oai:dash.harvard.edu:1/11744420
Date25 February 2014
CreatorsMartel, Joseph Maurice
ContributorsToner, Mehmet
PublisherHarvard University
Source SetsHarvard University
Languageen_US
Detected LanguageEnglish
TypeThesis or Dissertation
Rightsopen

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