Background: The five-factor model is the most prominent theory in personality science which aspire to understand the thoughts, feelings and behavior of individuals, determined by five relatively stable domains. Neuroticism, defined as a higher threat reactivity and susceptibility to negative affect, is one domain which has proven problematic for well-being, and has estimated societal costs of approximately 2.5 times that of common mental disorder per 1 million inhabitants. Problem: The neural correlates of neuroticism could supply research with a fundamental base of understanding the trait, however, due to scattered founding’s of segregated activity in brain structures relative to neuroticism, meta-analyses argue that increased understanding of global rather than local organization, could be more fruitful for the investigation. Methodology: Since neuroticism is convergent with emotional instability, two structures of interest with regards to global organization are the amygdala, crucial for emotion generation, and the prefrontal cortex (PFC), responsible for emotion interpretation and emotion regulation. Reviewing brain imaging research conducted with emphasis on integrative communication between the amygdala and the PFC in individuals with high trait neuroticism has therefore been the main objective of this thesis. Results/conclusion: According to the investigated research there is compromised structural integrity correlated with neuroticism, while the research on functional communication between the structures explored is not yet sufficiently covered to supply a satisfactory answer. Some of these neurobiological findings are in line with personality science observation in neuroticism, and could hence contribute to the investigation. However, more research is warranted in this field of neuroscience.
| Identifer | oai:union.ndltd.org:UPSALLA1/oai:DiVA.org:his-17458 |
| Date | January 2019 |
| Creators | Jedbäck, William |
| Publisher | Högskolan i Skövde, Institutionen för biovetenskap |
| Source Sets | DiVA Archive at Upsalla University |
| Language | English |
| Detected Language | English |
| Type | Student thesis, info:eu-repo/semantics/bachelorThesis, text |
| Format | application/pdf |
| Rights | info:eu-repo/semantics/openAccess |
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