A thesis submitted to the Faculty of Medicine, University of the
Witwatersrand, Johannesburg. in fulfilment of the requirements
of Doctor of Philosophy / Haemophilus influenzae and Haemophilus parainfluenzae are obligate
human parasites that form part of the flora of the mucous membranes.
They are normally present in the mouth and upper respiratory tract of
healthy individuals. H. influenzae is known as a major pathogen in
children while H. parainfluenzae is an opportunistic pathogen which is
also found in the urogenital tract. H. ducreyi, however; has only been
isolated from genital ulcers in patients suffering from chancroid. The
various species of the genus Haemophilus are characterised by their
requirements for two growth factors, X factor or haemin and V factor or
nicotinamide adenine dinucleotide (NAD). According to present
taxonomic criteria and laboratory practice, isolates belonging to the genus
Haemophilus that grow in the absence of NAD cannot be identified as H.
influenzae or H. poraintluenzae. However, in 1989 four unusual clinical
strains of H. parainfluenzae were isolated which were found to be V
factor-independent. (Abbreviation abstract) / Andrew Chakane 2019
| Identifer | oai:union.ndltd.org:netd.ac.za/oai:union.ndltd.org:wits/oai:wiredspace.wits.ac.za:10539/26628 |
| Date | January 1994 |
| Creators | Windsor, Helen Marie |
| Source Sets | South African National ETD Portal |
| Language | English |
| Detected Language | English |
| Type | Thesis |
| Format | application/pdf |
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