Thesis (S.M.)--Harvard-MIT Division of Health Sciences and Technology, 2010. / Cataloged from PDF version of thesis. / Includes bibliographical references (p. 41-44). / Collective intelligence techniques have been used to predict stock prices, customer purchasing habits, movies and books preferences for years, yet they remain unused in the medical profession. With the increasing adoption of electronic medical records, patients' medical data has grown exponentially and thus constitutes an untapped field where similar techniques could be applied. If data were collectively farmed and intelligently filtered, patient information could be added to traditional clinical decision support tools to arrive at personalized recommendations based on empiric evidence. The aim of this work is to use the collective, de facto, clinical experience to augment clinical guidelines thereby providing physicians with personalized clinical decision support. The pharmacological treatment of hypertension was chosen as the clinical domain in which to explore the feasibility of this approach. Twelve-thousand-three-hundred-forty-seven hypertensive patients were seen at the Internal Medical Associates (IMA) clinic at Massachusetts General Hospital (MGH) between July 2004 and September 2009. Their relevant clinical and demographic variables, drug regimens and blood pressure measurements were collected from the clinic's electronic medical record system and a dataset was generated. Back-end application software that draws upon case-based reasoning (CBR) was constructed and used to compute similarity between an index patient and existing hypertension patients. / (cont.) This program returned information regarding blood pressure control status and successful drug regimens used by similar patients. The use of EMR transactional data to provide a collective experience decision support (CEDSS) at the point-of-care using a computerized CBR approach is both technically possible and promising. Further studies are needed to evaluate the effectiveness of this method. / by Guido Alejandro Davidzon. / S.M.
| Identifer | oai:union.ndltd.org:MIT/oai:dspace.mit.edu:1721.1/57687 |
| Date | January 2010 |
| Creators | Davidzon, Guido Alejandro |
| Contributors | William Lester., Harvard University--MIT Division of Health Sciences and Technology., Harvard University--MIT Division of Health Sciences and Technology. |
| Publisher | Massachusetts Institute of Technology |
| Source Sets | M.I.T. Theses and Dissertation |
| Language | English |
| Detected Language | English |
| Type | Thesis |
| Format | 52 p., application/pdf |
| Rights | M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission., http://dspace.mit.edu/handle/1721.1/7582 |
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