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Statistical Analysis Of The Effects Of Atropine And Propranolol On The Inter-Beat Interval Of Rats

Heart rate variability (HRV) analysis has proved to be an important tool for assessing autonomic nervous system. For instance, it has been used during dipyridamole echocardiographic test to differentiate ischemic from nonischemic responses [6]. RR Interval analysis can provide additional information that can lead to early detection of a possible change in the activity of the autonomic nervous system. HRV analysis can be done using Wavelet Transform. This thesis presents a modification of an existing algorithm for extracting the R-R interval from EKG data sets and the use of wavelet transform (WT) technique to compute the timerequency domain energy quantities. The project used data obtained previously from a study of the effects of two pharmacological agents, atropine and propranolol, on laboratory rats. Results showed that the ratio of high frequency energy over the total energy (HF/total) of atropine treated rats was higher than baseline (control).

Identiferoai:union.ndltd.org:MSSTATE/oai:scholarsjunction.msstate.edu:td-5051
Date05 August 2006
CreatorsDahian, Abdud
PublisherScholars Junction
Source SetsMississippi State University
Detected LanguageEnglish
Typetext
Formatapplication/pdf
SourceTheses and Dissertations

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