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Targeting `Undruggable' Cancer Proteins with Irreversible Small Molecule Inhibitors: Her3 and KRas

With the lighting speed revolution of technologies in chemistry and biology, increasing number of proteins which eluded scientists' efforts to block them before and were labeled as `undruggable', were successfully targeted with small molecule inhibitors. During the past five years, I have been working on figuring out the path to inhibit two elusive cancer targets: Her3 and KRas. / Chemistry and Chemical Biology

Identiferoai:union.ndltd.org:harvard.edu/oai:dash.harvard.edu:1/12274197
Date January 2014
CreatorsXie, Ting
ContributorsGray, Nathanael Schiander
PublisherHarvard University
Source SetsHarvard University
Languageen_US
Detected LanguageEnglish
TypeThesis or Dissertation
Rightsclosed access

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