This thesis takes the DNA molecule and its circulation between scientific researchers as an object of analysis. The study's objective was to investigate the techno-social mechanisms through which certain individual's genetic materials are imputed with research value. Two cases, representing two contrasting kinds of circulation practices, are presented. In the first, DNA samples from families diagnosed with hereditary disorders, which allow researchers a shot at the all-or-nothing game of finding genes, are a protected resource. In the second, the DNA reference panel of the CEPH (Centre d'Etude du Polymorphisme Humain), made up of samples from large multi-generation families, is a widely distributed public resource. The CEPH panel was originally intended for use in genome mapping, but more recently has acted as a technology that aids in the innovation of new techniques and theories. It is argued that the difference in utility (limited or flexible) between these two types of DNA (privately or publicly held) is not found in any inherent property of the samples themselves but rather derives from the extent of the molecule's network of circulation.
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.29404 |
| Date | January 2001 |
| Creators | Poon, Martha A. |
| Contributors | Cambrosio, Alberto (advisor) |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Master of Arts (Department of Sociology.) |
| Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
| Relation | alephsysno: 001846981, proquestno: MQ80117, Theses scanned by UMI/ProQuest. |
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