He, Guoyun. / Thesis (M.Phil.)--Chinese University of Hong Kong, 2011. / Includes bibliographical references (leaves 62-69). / Abstracts in English and Chinese. / Title Page --- p.i / Abstract (English Version) --- p.iv / Abstract (Chinese Version) --- p.v / Acknowledgement --- p.vi / List of Tables --- p.ix / List of Figures --- p.x / List of Abbreviations and Symbols --- p.xii / Chapter Chapter One: --- Introduction --- p.1 / Chapter 1.1 --- Mismatches in DNA Duplex --- p.1 / Chapter 1.2 --- T.T Mismatches in DNA Duplex --- p.5 / Chapter 1.3 --- Purpose of the Work --- p.7 / Chapter 1.4 --- DNA Structure --- p.7 / Chapter 1.4.1 --- Structure and Nomenclature of Nucleotide --- p.7 / Chapter 1.4.2 --- Base Pairing --- p.8 / Chapter 1.4.3 --- Double Helical DNA Conformation --- p.9 / Chapter Chapter Two: --- Materials and Methods --- p.10 / Chapter 2.1 --- Sample Design --- p.10 / Chapter 2.2 --- Sample Preparation --- p.11 / Chapter 2.3 --- NMR Study --- p.11 / Chapter 2.3.1 --- Non-labile Proton Resonance Assignment --- p.12 / Chapter 2.3.2 --- Labile Proton Resonance Assignment in Normal Base Pairs --- p.13 / Chapter 2.3.3 --- Method to Determine T.T Pairing Mode --- p.14 / Chapter Chapter Three: --- Determination of T.T Pairing Mode --- p.16 / Chapter 3.1 --- NMR Resonance Assignment --- p.16 / Chapter 3.2 --- Result --- p.18 / Chapter 3.2.1 --- Preferential Pairing Mode: W --- p.18 / Chapter 3.2.2 --- Preferential Pairing Mode: W --- p.19 / Chapter 3.2.3 --- Exchanging and Pairing Modes --- p.20 / Chapter 3.3 --- Discussion --- p.23 / Chapter 3.3.1 --- Patterns of T.T Pairing Mode --- p.23 / Chapter 3.3.2 --- Reason for Preferential Pairing Mode --- p.24 / Chapter 3.3.3 --- Temperature Effect on T.T Pairing Mode --- p.26 / Chapter Chapter Four: --- Conclusions and Future Works --- p.29 / Chapter Appendix I: --- NOESY and WATERGATER-NOESY Assignment --- p.30 / Chapter Appendix II: --- Chemical Shifts of XTY --- p.46 / References --- p.62
| Identifer | oai:union.ndltd.org:cuhk.edu.hk/oai:cuhk-dr:cuhk_327519 |
| Date | January 2011 |
| Contributors | He, Guoyun., Chinese University of Hong Kong Graduate School. Division of Chemistry. |
| Source Sets | The Chinese University of Hong Kong |
| Language | English, Chinese |
| Detected Language | English |
| Type | Text, bibliography |
| Format | print, xii, 69 leaves : ill. ; 30 cm. |
| Rights | Use of this resource is governed by the terms and conditions of the Creative Commons “Attribution-NonCommercial-NoDerivatives 4.0 International” License (http://creativecommons.org/licenses/by-nc-nd/4.0/) |
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