The chemistry of a-hydroxylamino acids is critically reviewed. An attempt has been made to establish a general synthesis of a-hydroxylamino acids from a-bromo acids. A comparison of the use of cation and anion exchange columns as a means of purification has been included. The results of paper and thin layer chromatography of a-hydroxylamino acids have been reported. a-Hydroxylamine acids have been shown to be intermediates in the conversion of a-bromo acids to a-oximino acids with excess hydroxylamine. In addition, a new base-catalyzed decomposition of a-hydroxylamino acids to a-keto acids and ammonia is described. / Thesis / Master of Science (MS)
| Identifer | oai:union.ndltd.org:mcmaster.ca/oai:macsphere.mcmaster.ca:11375/24529 |
| Date | 12 1900 |
| Creators | Horning, Donald |
| Contributors | Spenser, I. D., Chemistry |
| Source Sets | McMaster University |
| Language | English |
| Detected Language | English |
| Type | Thesis |
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