Depletion of recombination-specific cofactors by the C-terminal mutant of the activation-induced cytidine deaminase causes the dominant negative effect on class switch recombination / AIDのC末端変異体は特異的共役因子を枯渇させるため、クラススイッチ組換えにドミナントネガティブ効果を及ぼす

Description

京都大学 / 0048 / 新制・課程博士 / 博士(医科学) / 甲第21030号 / 医科博第91号 / 新制||医科||6(附属図書館) / 京都大学大学院医学研究科医科学専攻 / (主査)教授 生田 宏一, 教授 清水 章, 教授 竹内 理 / 学位規則第4条第1項該当 / Doctor of Medical Science / Kyoto University / DFAM

Links & Downloads

1. http://hdl.handle.net/2433/232307
2. 14301甲第21030号
3. 10.14989/doctor.k21030
4. 14301

Tags

Heterogeneous nuclear ribonucleoproteins

Hyper IgM syndrome

CRISPR/Cas9 mutagenesis

CH12F3-2A B cell

AID-deficient spleen cells

491

Additional Fields

Identifer	oai:union.ndltd.org:kyoto-u.ac.jp/oai:repository.kulib.kyoto-u.ac.jp:2433/232307
Date	26 March 2018
Creators	Al, Ismail Azza Darwish
Contributors	生田, 宏一, 清水, 章, 竹内, 理, アッザ, アル イスマイル
Publisher	Kyoto University, 京都大学
Source Sets	Kyoto University
Language	English
Detected Language	English
Type	doctoral thesis, Thesis or Dissertation
Format	application/pdf
Rights	Educational Use; You may use the Article within your employer's institution or company for educational or research purposes only, including use in course-packs, as long as: (1) you do not use it for commercial purposes or re-distribution outside of the institution/company; (2) you acknowledge the Journal as the original place of publication with the correct citation details given.
Relation	https://doi.org/10.1093/intimm/dxx061