Oxidative stress (OS) and inflammation can be detrimental to exercise performance. Antioxidants such as curcumin are shown to reduce exercise-induced OS, inflammation, muscle damage, and soreness. The purpose of this study was to examine the effect of curcumin on biomarker markers of OS (MDA, TAC), inflammation (TNF-รก), muscle damage (CK) and soreness. Participants performed an exercise-induced muscle damage protocol. Before and after supplementation, subjects were randomly assigned to curcumin (1.5 g/day) or placebo for 28 days. Blood was sampled immediately before and after exercise, as well as 60 min, 24, and 48 h after exercise. No significant differences were observed for biomarkers of OS or inflammation. There was a treatment X condition interaction for CK, where CK were significantly lower post supplementation in the curcumin group (p < .0.0001). Curcumin resulted in significantly lower muscle soreness compared to the placebo (p = 0.0120) overall. In conclusion, curcumin may reduce muscle damage, and soreness without affecting the natural OS and inflammatory response to exercise.
| Identifer | oai:union.ndltd.org:MSSTATE/oai:scholarsjunction.msstate.edu:td-2649 |
| Date | 04 May 2018 |
| Creators | Basham, Steven Allen |
| Publisher | Scholars Junction |
| Source Sets | Mississippi State University |
| Detected Language | English |
| Type | text |
| Format | application/pdf |
| Source | Theses and Dissertations |
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