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A study of the molecular and biological characteristics of ovine interleukin-12 / Sarah Jane Swinburne.

Bibliography: leaves 172-214. / 214 leaves, [41] leaves of plates : ill. (some col.) ; 30 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Interleukin-12 (IL-12) is a heterodimeric cytokine composed of two disulphide-linked subunits, p35 and p40, which form biologically active p70. IL-12 is able to induce IFN-y production from T and NK cells, and promote the proliferation of mitogen-activated T cells. It is thought that IL-12 may be an important cytokine in the initiation and progression of allograft destruction. This thesis describes the characterisation of ovine IL-12. / Thesis (Ph.D.)--University of Adelaide, Dept. of Medicine, 2000

Identiferoai:union.ndltd.org:ADTP/260986
Date January 2000
CreatorsSwinburne, Sarah Jane
Source SetsAustraliasian Digital Theses Program
Languageen_US
Detected LanguageEnglish

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