The corner-stone of the Renin-Angiotensin System was laid down almost seven decades ago when Tigerstedt and Bergman gave the name "Renin" to the pressor substance they had discovered in kidney extracts (1). However, this discovery was forgotten for many years before its importance was recognized. This recognition came in 1934 when Goldblatt demonstrated the role of the kidney in the pathogenesis of a certain type of hypertension (2) and especially after it appeared that the renal pressor substance might be involved in the pathogenesis of experimental and human hypertension. Thereafter, for many years, the renin-angiotensin system became closely and almost exclusively associated with the field of hypertension. [...]
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.116835 |
| Date | January 1965 |
| Creators | de Champlain, Jacques. |
| Contributors | Genest, J. (Supervisor), Browne, J. S. L., Veyrat, Robert. |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Doctor of Philosophy. (Department of Investigative Medicine. ) |
| Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
| Relation | alephsysno: NNNNNNNNN, Theses scanned by McGill Library. |
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