Hormones are typically considered to be chemical messengers, which are designed to be released from specific cells where they are carried to their target tissues for binding to receptors. It is this binding of a hormone molecule to its specific receptor which allows for an action to occur (Hadley and Levine 2006). Testosterone is the predominant androgen in the majority of mammalian species and is largely responsible for regulation of reproduction and maintenance of sexual function. In addition, in adult mammals, T has multiple other roles including the growth of muscle and bone, hematopoesis, blood coagulation, development and regulation of plasma lipids, protein and carbohydrate metabolism, and cognitive function (Bhasin, 2005). Cortisol has typically been thought of as a suppressor of the immune system and an anti-inflammatory agent as it is an inducer of cellular apoptosis. In research where corticosteroids were given intravenously to humans, responses of apoptosis of T and B cells were noted (Cohen and Duke 1984).
Testosterone and C as well as other hormones have received significant attention in recent years by several researchers who have proposed a link between these hormones and performance, adaptive capability, and overtraining syndrome (Kraemer & Ratamass, 2005). The use of T to C ratio (T/C) has gained some popularity in recent years as a method to monitor anabolic/catabolic state in athletes, and to predict athletic performance and/or overtraining. There is a growing body of evidence that T/C may be useful in monitoring training stress and physiological phenomenon, however, the relationship between these variables and any actual physical performance has not been solidly established at this time.
| Identifer | oai:union.ndltd.org:LSU/oai:etd.lsu.edu:etd-08162008-123732 |
| Date | 22 August 2008 |
| Creators | Winchester, Jason B |
| Contributors | Arnold G. Nelson, Dennis Landin, Laura K. Stewart, Michael H. Stone, Anne Grove |
| Publisher | LSU |
| Source Sets | Louisiana State University |
| Language | English |
| Detected Language | English |
| Type | text |
| Format | application/pdf |
| Source | http://etd.lsu.edu/docs/available/etd-08162008-123732/ |
| Rights | unrestricted, I hereby certify that, if appropriate, I have obtained and attached herein a written permission statement from the owner(s) of each third party copyrighted matter to be included in my thesis, dissertation, or project report, allowing distribution as specified below. I certify that the version I submitted is the same as that approved by my advisory committee. I hereby grant to LSU or its agents the non-exclusive license to archive and make accessible, under the conditions specified below and in appropriate University policies, my thesis, dissertation, or project report in whole or in part in all forms of media, now or hereafter known. I retain all other ownership rights to the copyright of the thesis, dissertation or project report. I also retain the right to use in future works (such as articles or books) all or part of this thesis, dissertation, or project report. |
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