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Modeling Cancer Cell Response to Immunotherapy

Significant work has been done modeling cancerous tumor growth and response to therapy under certain simplifying assumptions, specifically, the assumption of spatial homogeneity. We have chosen a spatially heterogenous model for cancer cell growth using a hybrid Lattice-Gas Cellular Automata method. Cell mitosis, apoptosis, and necrosis are explicitly modeled along with the diffusion of nutrients and a necrotic signal. The model implementation is verified qualitatively and is modified to execute on a parallel computer.

Identiferoai:union.ndltd.org:CLAREMONT/oai:scholarship.claremont.edu:hmc_theses-1167
Date01 May 2004
CreatorsHarley, Eric
PublisherScholarship @ Claremont
Source SetsClaremont Colleges
Detected LanguageEnglish
Typetext
Formatapplication/pdf
SourceHMC Senior Theses

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