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Permeability of cerebral blood vessels to protein molecules in convulsive seizures.

Histological examination of the brains of experimental animals subjected to convulsive seizures shows an evidence of tissue damage which could be the result, to some extent, of increased vascular permeability. Diapedesis of red cells, edema and nerve cell damage in acute stages, and perivascular hematogenous pigment, nerve cell deficit and gliosis around the blood vessels in chronic conditions are examples of such changes. More direct evidence was obtained in experiments in which trypan blue was used to test the permeability of the blood-brain barrier (BBB) in various pathological conditions - among others, in the electrically-induced epileptic seizures.

Identiferoai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.110302
Date January 1956
CreatorsRozdilsky, Bohdan.
ContributorsOlszewski, J. (Supervisor)
PublisherMcGill University
Source SetsLibrary and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada
LanguageEnglish
Detected LanguageEnglish
TypeElectronic Thesis or Dissertation
Formatapplication/pdf
CoverageMaster of Science. (Department of Neurology and Neurosurgery)
RightsAll items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated.
Relationalephsysno: NNNNNNNNN, Theses scanned by McGill Library.

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