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Presentation of intracranial meningiomas in Johannesburg (a 12-month prospective study at Charlotte Maxeke Johannesburg Academic Hospital and Chris Hani Baragwanath Hospital)

The study aimed at determining the relative frequency of intracranial meningiomas among primary brain tumours; age, gender, ethnic distributions and their mode of presentation.
This was a 12-month prospective study of 48 consecutive patients with histologically proven intracranial meningiomas seen at CMJAH and CHBH.
Meningiomas accounted for 33.8% of all primary brain tumours. The mean age of patients was 45.7 ± 10.1 years with a female-to-male ratio of 3.8:1. The peak age range at presentation was in the fifth (41.7%) and sixth (27.1%) decades. The highest frequency was in Blacks (75%) and Sotho ethnic nationality (27.1%). The mean duration of symptoms and signs was 24.4 ± 26.5 months. The commonest presentations were headache (87.5%), visual impairment (64.6%), seizures (43.8%), motor deficit (37.5%), convexity meningiomas (25%), meningothelial subtypes (39.6%) and WHO grade I tumours (81.3%).
This study showed that meningiomas are the most common primary intracranial tumours among adults in our environment.

Identiferoai:union.ndltd.org:netd.ac.za/oai:union.ndltd.org:wits/oai:wiredspace.wits.ac.za:10539/12548
Date18 March 2013
CreatorsIbebuike, Kaunda Emeka
Source SetsSouth African National ETD Portal
LanguageEnglish
Detected LanguageEnglish
TypeThesis
Formatapplication/pdf

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