<p>Formal thought disorder (FTD) is a debilitating symptom of
psychosis. It is linked to functional deficits and generally demonstrates poor
response to interventions. Metacognition has emerged as a potential therapeutic
target that may be effective in reducing FTD, as metacognitive deficits and FTD
both arise from disruptions in associative thought processes. This study’s
primary aim was to determine whether FTD could be reduced with metacognitive
therapy. Pre-post changes in FTD severity were assessed using clinician-rated
and automated measures in 20 individuals with psychotic disorders who received
12 sessions of evidence-based metacognitive therapy. We also examined whether
reductions in FTD were larger when assessed with automated instruments versus
clinician-rated measures. Aim two compared associations between FTD and three
outcome variables (social functioning, role functioning, metacognition) across
FTD-measurement approach. Results indicated that automated FTD, but not
clinician-rated FTD, was significantly reduced post-intervention. This effect
was more robust within a subsample exhibiting greater levels of FTD. Strength
of associations between FTD and outcome variables did not differ across FTD
measurement approach. These findings provide initial evidence that a targeted
metacognitive intervention can reduce FTD. Effects were strongest for automated
instruments, which may be more sensitive to detecting change; however,
differences in measurement type did not extend to associations with selected
outcome variables. This study provides preliminary support for future efforts
to reduce FTD. Large-scale studies with longer intervention periods may further
our understanding of the effectiveness of metacognitive intervention on FTD. </p>
| Identifer | oai:union.ndltd.org:purdue.edu/oai:figshare.com:article/12721685 |
| Date | 29 July 2020 |
| Creators | Matthew Paul Marggraf (9173894) |
| Source Sets | Purdue University |
| Detected Language | English |
| Type | Text, Thesis |
| Rights | CC BY 4.0 |
| Relation | https://figshare.com/articles/thesis/Addressing_Formal_Thought_Disorder_in_Psychosis_through_Novel_Assessment_and_Targeted_Intervention/12721685 |
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