Return to search

Genomic insights into bacterial adaptation during infection

Bacteria evolve during the colonization of human hosts, yet little is known about the selective pressures and evolutionary forces that shape this evolution. Illumination of these processes may inspire new therapeutic directions for combating bacterial infections and promoting healthy bacteria-host interactions. The advent of high-throughput sequencing has enabled the identification of mutations that occur within the human host, and various tools from computational and evolutionary biology can aid in creating biological understanding from these mutations. Chapter 1 describes recent progress in understanding within-patient bacterial adaption, focusing on insights made from genomic studies.

Identiferoai:union.ndltd.org:harvard.edu/oai:dash.harvard.edu:1/12274588
Date04 June 2015
CreatorsLieberman, Tami Danielle
ContributorsKishony, Roy
PublisherHarvard University
Source SetsHarvard University
Languageen_US
Detected LanguageEnglish
TypeThesis or Dissertation
Rightsopen

Page generated in 0.0017 seconds