In this study, we examined survival for patients with micrometastases greater than 0.2mm but less than 2mm (pN1a) in comparison to node-negative (pN0) and macrometastatic node-positive (pN1b) patients. Data for patients diagnosed from 1988 to 1998 with TNM pathological T1-2 stage, pN0, and pN1a-b breast cancer with no distant metastasis was provided by Dr. P. Truong from BC Cancer Agency. Results obtained from the Kaplan-Meier estimators and the multivariable Cox Proportional Hazards Model analyses suggested that micrometastatic node-positive patients had worse survival than the node-negative patients, but better survival in comparison to the macrometastatic node-positive patients. Increasing number of positive nodes and larger values of the ratio of positive to excised nodes were significantly associated with worse survival.
| Identifer | oai:union.ndltd.org:uvic.ca/oai:dspace.library.uvic.ca:1828/1393 |
| Date | 30 April 2009 |
| Creators | Li, Karen Hui |
| Contributors | Lesperance, M. L. |
| Source Sets | University of Victoria |
| Language | English, English |
| Detected Language | English |
| Type | Thesis |
| Rights | Available to the World Wide Web |
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