Muscotoxins: novel cytotoxic undecapeptides with unique structural elements and mechanism of action, isolated from soil cyanobacterium \kur{Nostoc muscorum.} / Muscotoxins: novel cytotoxic undecapeptides with unique structural elements and mechanism of action, isolated from soil cyanobacterium \kur{Nostoc muscorum}

Description

This project was focused on development of extraction and purification protocol for novel cytotoxic compound isolated from soil cyanobacterium Nostoc muscorum which would allow to determine its molecular structure via NMR (nuclear magnetic resonance) and MS (mass spectrometry) techniques. Purified cytotoxin was subjected to several biochemical and microscopical experiments in order to assess its toxicological parameters, determine the mechanism of action and evaluate potential application in biotechnology or pharmacy.

Links & Downloads

1. http://www.nusl.cz/ntk/nusl-53236

Tags

Additional Fields

Identifer	oai:union.ndltd.org:nusl.cz/oai:invenio.nusl.cz:53236
Date	January 2010
Creators	TOMEK, Petr
Source Sets	Czech ETDs
Language	Czech
Detected Language	English
Type	info:eu-repo/semantics/masterThesis
Rights	info:eu-repo/semantics/restrictedAccess