The £\-helix structure of protein is very similar to the cylindrical structure. Especially, the Sperm-Whale Myoglobin molecules has 70% £\-helix structure. Therefore, we use simulated annealing method to solve ¡§X-ray phase problem¡¨, and apply Metropolis algorithm to avoid local minimum. We hope that the new method can build £\-helix structure of Sperm-Whale Myoglobin molecule.
Therefore, we use multi cylinders as the Myoglobin¡¦s tertiary structure and solve the cylinder¡¦s structure with the simulated annealing method.
Identifer | oai:union.ndltd.org:NSYSU/oai:NSYSU:etd-0717102-154451 |
Date | 17 July 2002 |
Creators | Chen, Chien-Cheng |
Contributors | Herng-Yih Ueng, Wang-Chuang Kuo, Chiang Michael Yen-Nan |
Publisher | NSYSU |
Source Sets | NSYSU Electronic Thesis and Dissertation Archive |
Language | Cholon |
Detected Language | English |
Type | text |
Format | application/pdf |
Source | http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0717102-154451 |
Rights | withheld, Copyright information available at source archive |
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