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Preparation of N-Substituted Hydroxylamines from Oxaziridines

In many series of compounds, intensity of biological activity and chemical reactivity are proportional. Generally whenever a alkyl group replaces a reactive hydrogen atom, as would be the case for an N-substituted hydroxylamine as compared to hydroxylamine, the over-all biological activity of the resulting compound is lower than that of its nonalkylated analogue. Since toxicity and physiological activity are not proportional, this comparison can only suggest possible types of derivatives to prepare and test.

Identiferoai:union.ndltd.org:unt.edu/info:ark/67531/metadc130926
Date01 1900
CreatorsTruitt, Sharon G.
ContributorsTruitt, Price, York, Carl T.
PublisherNorth Texas State University
Source SetsUniversity of North Texas
LanguageEnglish
Detected LanguageEnglish
TypeThesis or Dissertation
Formatiii, 29 leaves: ill., Text
RightsPublic, Copyright, Copyright is held by the author, unless otherwise noted. All rights reserved., Truitt, Sharon G.

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