<p> </p>
<p>Conventional clinical therapies for head and neck squamous cell carcinomas (HNSCC) include surgical resection, chemotherapy (CT), and radiotherapy (RT). For locally advanced HNSCC, the CT-RT combination (“chemoradiation”) has been shown to be more effective than CT or RT alone and is the current standard of care. A novel radiation-controlled drug release nanoparticle formulation has been developed to realize the maximum benefits of intratumoral CT-RT. Under the application of low-dose X-ray, the formulation is capable of releasing PTX and providing localized, controlled, and sustained drug release for improvements in therapeutic efficacies.</p>
Identifer | oai:union.ndltd.org:purdue.edu/oai:figshare.com:article/20405805 |
Date | 29 July 2022 |
Creators | Kaustabh Sarkar (13171509) |
Source Sets | Purdue University |
Detected Language | English |
Type | Text, Thesis |
Rights | CC BY 4.0 |
Relation | https://figshare.com/articles/thesis/RADIOLUMINESCENT_NANOPARTICLES_FOR_MULTIMODAL_CANCER_TREATMENT/20405805 |
Page generated in 0.0016 seconds