Multifunctional theranostic nanoparticles hold promise for enabling non-invasive image guided cancer therapy such as photothermal therapy. Human breast tumor models in which response to image guided therapy can quickly and non-invasively be determined are needed to facilitate translation and application of these technologies. We hypothesize that a system utilizing a murine light-reporter mammary tumor cell line and near-infrared nanoparticles (NIR-NP) can be used to quantify response to therapy and determine fate of nanoparticles following photothermal ablation.
| Identifer | oai:union.ndltd.org:ETSU/oai:dc.etsu.edu:etsu-works-17905 |
| Date | 09 November 2010 |
| Creators | Gutwein, L., Singh, A. K., Hahn, M., Rule, M., Brown, S., Knapik, J., Moudgil, B., Grobmyer, S. |
| Publisher | Digital Commons @ East Tennessee State University |
| Source Sets | East Tennessee State University |
| Detected Language | English |
| Type | text |
| Source | ETSU Faculty Works |
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