Objectives: The aim of this study was to determine the prevalence of MetS among
different African populations using the new Joint Statement Criteria. Hereafter we
aimed to determine whether waist or neck circumference is the best predictor of
MetS risk after ethnic, gender and age-specific cut-points were developed. Lastly, we
aimed to determine whether afore-mentioned cut-point can predict
albumin:creatinine ratio as a marker of target organ damage. Methods: The study
sample (N=409) comprised of urban African (men, N=101; women, N=99) and
Caucasian (men, N=101; women, N=108) teachers from the Dr. Kenneth Kaunda
Education district in the North-West Province, South Africa. Participants were aged
between 25 and 65 years. Anthropometric measurements, albumin:creatinine ratio
and other markers of the metabolic syndrome (MetS) (systolic and diastolic blood
pressure [SBP and DBP], glucose, triglycerides [TG] and high density lipoprotein
[HDL]) were determined. Results: Africans (65 and 63 % for men and women) and
Caucasian men (73%) showed high prevalence of MetS; ROC analysis determined
neck circumference (NC) cut-points of 39 and 35 cm for young and older African
men, 32 and 35 cm for young and older African women, 40 and 41 cm for Caucasian
men and 34 and 33 cm for Caucasian women. This NC cut-point can be used to
determine metabolic syndrome risk in all groups, except in African women; ROC
developed waist circumference (WC) cut-points were 91 cm for all African male
groups, 84, 81 and 84 cm for young, older and total group of African women.
Suggested WC cut-points for Caucasian men were 93 cm for the young group and
97 cm for older as well as total Caucasian male groups, while cut-points for
Caucasian women were 87 cm, 79 cm and 84 cm for young, older and total
Caucasian women. These WC cut-points were good measures of metabolic
syndrome risk in all groups; neither cut-point of WC nor NC could increase the risk of
albumin:creatinine ratio. Conclusion: African women as a group present with few
MetS risk factors and glucose is associated with renal function risk in Africans; NC
cut-points may be used as an additional anthropometric marker to predict the
metabolic syndrome in a South African cohort, but not in African women; WC cutpoints
demonstrated to be good predictors of the metabolic syndrome in the same South African cohort, especially among men; WC would seem to be the best
measure of MetS risk in all African populations, although NC can also be used for
this purpose in all African populations, except in African women. / Thesis (PhD (Human Movement Science))--North-West University, Potchefstroom Campus, 2012
| Identifer | oai:union.ndltd.org:netd.ac.za/oai:union.ndltd.org:nwu/oai:dspace.nwu.ac.za:10394/8483 |
| Date | January 2012 |
| Creators | Hoebel, Svelka |
| Publisher | North-West University |
| Source Sets | South African National ETD Portal |
| Language | English |
| Detected Language | English |
| Type | Thesis |
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