Parkinson’s disease (PD) has devastating effects that include both motor and non-motor impairments. Advanced medicine including pharmacotherapy and surgical options have made it possible for individuals that hold this diagnosis to live somewhat normal lives. As treatment options for this disease have been further investigated, exercise has been found to have benefit by preserving function and quality of life for Parkinson’s patients.
Although the positive effects of exercise on Parkinson’s patients have been explored, the exact type and how much has not been narrowed down. Not one form of exercise can be said to be more efficacious than another for patients with Parkinson’s disease. In addition, exercise has not been thoroughly analyzed in the long term for patients with Parkinson’s disease.
An exercise modality that recently has gained popularity due to its benefits is high intensity interval training (HIIT). This modality of exercise allows modifiable and accessible training sessions that improve cardiorespiratory fitness. Its benefit has extended to individuals with chronic disease but not robustly in the Parkinson’s population.
The proposed study below will consist of a randomized control trial in people with Parkinson’s disease comparing a 24-month HIIT program to a control group. Symptoms will be scored on the movement disorder society’s unified Parkinson’s disease rating scale (MDS-UPDRS) at baseline, throughout and after treatment and further analyzed to see if there is clinical significance in using this type of exercise in this population. If HIIT proves its efficacy in this study, it allows clinicians more insight on the most appropriate treatment for Parkinson’s patients.
| Identifer | oai:union.ndltd.org:bu.edu/oai:open.bu.edu:2144/46335 |
| Date | 13 June 2023 |
| Creators | Varden, Aine |
| Contributors | Hohler, Anna D., Weinstein, John |
| Source Sets | Boston University |
| Language | en_US |
| Detected Language | English |
| Type | Thesis/Dissertation |
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