Cancer is the second leading cause of death in females. According to the American
Cancer Society, there are 327,660 new cases in breast and gynecological cancers
estimated in 2014, placing emphasis on the need for cancer prevention and new cancer
treatment strategies. One important approach to cancer prevention involves phytochemicals,
biologically active compounds derived from plants. A variety of studies on the
impact of dietary compounds found in cruciferous vegetables, green tea, and spices like
curry and black pepper have revealed epigenetic changes in female cancers. Thus, an
important emerging topic comprises epigenetic changes due to the modulation of noncoding
RNA levels. Since it has been shown that non-coding RNAs such as microRNAs
and long non-coding RNAs are aberrantly expressed in cancer, and furthermore are
linked to distinct cancer phenotypes, understanding the effects of dietary compounds and
supplements on the epigenetic modulator non-coding RNA is of great interest. This article
reviews the current findings on nutrition-induced changes in breast and gynecological
cancers at the non-coding RNA level.
| Identifer | oai:union.ndltd.org:DRESDEN/oai:qucosa:de:qucosa:80358 |
| Date | 10 August 2022 |
| Creators | Krakowsky, Rosanna H.E., Tollefsbol, Trygve O. |
| Publisher | Frontiers Media |
| Source Sets | Hochschulschriftenserver (HSSS) der SLUB Dresden |
| Language | English |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, doc-type:article, info:eu-repo/semantics/article, doc-type:Text |
| Rights | info:eu-repo/semantics/openAccess |
| Relation | 16 |
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