Dietary carbohydrate during pregnancy is essential but whether this requirement is specific to glucose or if fructose could substitute for glucose in the diet of pregnant rat dams was investigated. It was concluded that the carbohydrate requirement for the rat during pregnancy is not specific to glucose and the level, not the type, of carbohydrate was critical. The potential toxicity of high fructose diets was also investigated. Dams fed high fructose had significantly higher liver weights than dams fed high glucose while other toxic indicators were not affected. A third aspect was the comparison of isocaloric, low carbohydrate diets containing different sources of 4% glucose equivalents: glucose, fructose or lipid-glycerol. Fructose and lipid-glycerol were not adequate substitutes for glucose. The measurement of amniotic fluid glucose, which increased as either dietary glucose or fructose increased in the maternal diet may be a new, accessible nutritional indicator of carbohydrate status.
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.59400 |
| Date | January 1989 |
| Creators | Fergusson, Marjorie |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Master of Science (School of Dietetics and Human Nutrition.) |
| Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
| Relation | alephsysno: 001070015, proquestno: AAIMM63570, Theses scanned by UMI/ProQuest. |
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