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MERGING OMNIPHOBIC LUBRICANT-INFUSED COATINGS WITH DIFFERENT MICROFLUIDIC MODALITIES TO ENHANCE DEVICE FABRICATION AND FUNCTIONALITY

Surface science is a multidisciplinary subject which affects us on
a daily basis. Surfaces are of particular interest because the
chemical bonding and atomic structure is different at the surface
compared to the bulk properties of a material. This interface is of
great significance because it is where charge exchange, or new
chemical bonds occur. One essential aspect of surface science is
surface wettability, which can be harnessed to produce self-cleaning
surfaces. This very lucrative notion, where surfaces with low
adhesion to liquids, can result in quick and autonomous shedding,
has inspired a multitude of device fabrication and implementation.
Over the past decade, several self-cleaning surfaces have been
fabricated from superhydrophobic surfaces, which depends on a
stable interface between solid, liquid and gas. These surfaces,
however, are restricted in their applications and fail to operate upon
mechanical damage or nonhomogeneous fabrication processes.
Recent advances in wettability science have produced omniphobic
lubricant-infused surfaces (OLIS). These surfaces are created by
tethering a liquid to a surface, providing a stable liquid interface, which results in excellent aqueous and organic liquid repellency, and high
robustness toward physical damage. This thesis will encompass an
overview of the classical models for surface wettability, new models
for liquid mobility, the criteria required to obtain OLIS, as well as
some of the biomedical engineering applications fabricated from this
technology. Herein, a novel manufacturing process was developed to
produce smooth channeled polymeric microfluidic devices from rough
3D printed molds. Additionally, we integrated OLIS technology with
electroconductive sensors to create high surface area electroactive
material with self-cleaning properties, ideal to combat non-specific
adhesion of biomolecules. Furthermore, our fabrication methods
are inexpensive and have the potential to be easily integrated
into manufacturing processes to create highly functional microfluidic
devices, optimal for lab-on-chip diagnostic platforms. / Thesis / Master of Applied Science (MASc) / Recent advances in wettability science have produced omniphobic
lubricant-infused surfaces (OLIS) inspired by the Nepenthes pitcher
plant. These surfaces are created by tethering a liquid to a surface,
providing a stable liquid interface, which results in excellent aqueous
and organic liquid repellency, as well high robustness toward physical
damage and high pressure dispensing scenarios.
The motivation for this thesis is to expand on the applications for OLIS
devices. Herein, a novel manufacturing process was developed to
produce smooth channeled polymeric microfluidic devices from rough
3D printed molds. Additionally, we integrated OLIS technology with
electroconductive sensors to create high surface area electroactive
material with self-cleaning properties, ideal to combat non-specific
adhesion of biomolecules.

Identiferoai:union.ndltd.org:mcmaster.ca/oai:macsphere.mcmaster.ca:11375/23024
Date January 2018
CreatorsVillegas, Martin
ContributorsDidar, Tohid, Biomedical Engineering
Source SetsMcMaster University
LanguageEnglish
Detected LanguageEnglish
TypeThesis

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