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Modelling the cochlear origins of distortion product otoacoustic emissions

Distortion product otoacoustic emissions (DPOAEs) arise within the cochlea in response to two stimulus tones (f1 and f2) at frequencies such as 2f1 − f2 and 2f2 − f1. Each DPOAE derives from two contributing mechanisms within the cochlea: a distributed distortion source and a reflection source. They are used for hearing screening, but a better understanding of their cochlear origin and transmission could potentially extend their clinical application to facilitate objective hearing loss assessment, differential diagnosis of sensorineural hearing losses and improved auditory rehabilitation using hearing aids. In this thesis a numerical model of the human cochlea is developed to study the generation of DPOAEs. It is based on a pre-existing active nonlinear model, the micromechanics of which are carefully re-tuned to simulate the response of the human cochlea to single- and two- tone stimulation. Particular attention is paid to the form and position of the nonlinearity within the model to best match experimental results. The model is also reformulated to verify its stability and ensure computational convergence of the iterative frequency domain solution method. Its predictions are validated against estimated time domain simulations and documented experimental DPOAE measurements. Additionally a novel method is developed for decomposing each frequency component of the cochlear response into forward and backward travelling waves, which is applied to investigate the multiple sources of both the 2f1 − f2 and 2f2 − f1 DPOAEs. The model is used to explain and predict a variety of phenomena observed in experimental DPOAE studies. It also confirms for the 2f1 − f2 emission, that the two source mechanisms are spatially separated and that the only significant reflection contribution is associated with the 2f1 − f2 travelling wave. In contrast, it predicts that the two source mechanisms will overlap in the case of the 2f2 − f1 DPOAE, which can be influenced by reflection of both the primary and 2f2 − f1 travelling waves.

Identiferoai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:536377
Date January 2011
CreatorsYoung, Jacqueline Ann
ContributorsElliott, Stephen
PublisherUniversity of Southampton
Source SetsEthos UK
Detected LanguageEnglish
TypeElectronic Thesis or Dissertation
Sourcehttps://eprints.soton.ac.uk/175357/

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