Vanadium haloperoxidases (VHPOs) are enzymes that catalyse the oxidation of halide ions to hypohalous acids by hydrogen peroxide. There are many unanswered questions on the mechanism by which the oxidation reaction occurs. In this work, is reported the synthesis of [VO(O2)H2EDTA], studies of the effect of acid concentration on the decomposition of [VO(O2)HEDTA]-2, and mechanistic studies of the rate law. The decomposition reaction was found to be first order with respect to acid concentration and also [VO(O2)HEDTA]-2 concentration. The reaction of [VOHEDTA]-1 and hydrogen peroxide progressed via a free radical path way. In addition, the vanadium(V) complex [VO(O2)H2EDTA] was synthesized and characterised by FT-IR, UV-VIS and GC-MS. The catalytic properties of [VO(O2)H2EDTA] were investigated for an oxibromination reaction. It was found that the catalysed, and the control reaction showed no major differences except for the fact that the reaction with the catalyst gave a dibrominated product without a carbonyl group.
| Identifer | oai:union.ndltd.org:ETSU/oai:dc.etsu.edu:etd-3785 |
| Date | 01 August 2014 |
| Creators | Fon, Tinga C. O., Mr. |
| Publisher | Digital Commons @ East Tennessee State University |
| Source Sets | East Tennessee State University |
| Detected Language | English |
| Type | text |
| Format | application/pdf |
| Source | Electronic Theses and Dissertations |
| Rights | Copyright by the authors. |
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