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Isoniazid preventive therapy in HIV infected children on antiretroviral therapy living in a high tuberculosis prevalence area a randomized controlled trial

Includes bibliographical references. / Tuberculosis (TB) and HIV are dual epidemics and a public health crisis in Southern Africa. An estimated 2.5 million children are living with HIV, of which 2.3 million live in Sub-Saharan Africa, with an estimated 230 000 child deaths from AIDS. In 2010 there were an estimated 8 million incident cases of tuberculosis (TB) globally, 1.2 million amongst people living with HIV. Over 1 million TB related deaths occurred, a third of which occurred amongst people living with HIV.[4] The African region accounts for 26% of the global TB burden and 82% of the TB cases among people living with HIV. TB and HIV are a deleterious combination. TB is a common cause of acute and chronic respiratory disease and a leading cause of death amongst HIV infected children in TB endemic areas.

Identiferoai:union.ndltd.org:netd.ac.za/oai:union.ndltd.org:uct/oai:localhost:11427/10538
Date January 2012
CreatorsGray, Diane Margaret
ContributorsZar, Heather
PublisherUniversity of Cape Town, Faculty of Health Sciences, Department of Paediatrics and Child Health
Source SetsSouth African National ETD Portal
LanguageEnglish
Detected LanguageEnglish
TypeMaster Thesis, Masters, MPhil
Formatapplication/pdf

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