Tetrahydroisoquinoline alkaloids are a class of structurally complex natural products and a huge number of its natural product widely exist in nature which, from the discovery has been more than a century, it compounds with high anti-tumor activity, antibacterial and other physical activity, but also because of its special structure, with low oncentration of biological activity, but these alkaloids are not sold in the market mainly due to a less natural extraction, chemical synthesis method and multi-step, low yield.
Therefore, we constructed a combination of tetrahydroisoquinoline alkaloids and the pyrazino [2,1-b] quinazoline-3,6-diones structure of the new compounds, which have the quinazolinone compounds which is the drug synthesis and drug activity on the bond, is also a kind of unique and widely
used drug structure, and causes a lot of scientists and drug research interest and discussion, as we develop the motivation.
| Identifer | oai:union.ndltd.org:NSYSU/oai:NSYSU:etd-0823110-165622 |
| Date | 23 August 2010 |
| Creators | Yang, Ping-Syun |
| Contributors | Jeh-Jeng Wang, Chi-wi Ong, Ming-Jung Wu |
| Publisher | NSYSU |
| Source Sets | NSYSU Electronic Thesis and Dissertation Archive |
| Language | Cholon |
| Detected Language | English |
| Type | text |
| Format | application/pdf |
| Source | http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0823110-165622 |
| Rights | not_available, Copyright information available at source archive |
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