This study attempts to develop a method for absolute
quantitation in Positron Emission Tomography. This includes the
definition of the dimension and the position of a tumour in the
brain as well as the evaluation of the amount of drug delivered
to the tumour and to surrounding tissues in a pixel-by-pixel way,
from the image. The defined objectives can be achieved using the
calibrated FWHM values of the distribution of events in the tumour
image, versus distance, to determine the dimension and the
position of the tumour. The concentration activity in the tumour
and the tumour-to-nontumour activity ratios can be obtained from
the image, using a modified filter and the calibration of the
tomograph. The colour scale of the image can be expressed in
absolute units (μCi/ml) and the concentration activity can be
evaluated in each pixel of the image or in each volume element of
the body. / Thesis / Master of Science (MS)
| Identifer | oai:union.ndltd.org:mcmaster.ca/oai:macsphere.mcmaster.ca:11375/24225 |
| Date | 08 1900 |
| Creators | Popescu, Alina |
| Contributors | Nahmias, C., Physics |
| Source Sets | McMaster University |
| Language | English |
| Detected Language | English |
| Type | Thesis |
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