Submitted by Sandra Pereira (srpereira@ufrrj.br) on 2018-04-11T13:17:41Z
No. of bitstreams: 1
2010 - Bruno Leite dos Anjos.pdf: 12893665 bytes, checksum: 99b4dd0f8ecdebb1f227aa0522ac061f (MD5) / Made available in DSpace on 2018-04-11T13:17:42Z (GMT). No. of bitstreams: 1
2010 - Bruno Leite dos Anjos.pdf: 12893665 bytes, checksum: 99b4dd0f8ecdebb1f227aa0522ac061f (MD5)
Previous issue date: 2010-08-17 / Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico, CNPq, Brasil. / Cases of diseases induced by toxic plants in domestic herbivores are well reported throughout
the world and have been studied also in Brazil. However, not much is known about the
epidemiological and pathological aspectos of these conditions in free-living wildlife or bred in
captivity. The risk for developing the toxicoses in captivity has been increasing, since natural
habitats are destroyed by human action, and more centers of wildlife conservation and
zoological comes are created. This study describes the epidemiological, biological and
clinicopathological, lectin-histochemical and ultrastructural aspects of an outbreak of
lysosomal storage disease of oligosaccharides induced by ingestion of Sida carpinifolia in
young Sambar deer (Cervus unicolor) in the Rio-Zoo Foundation in the State of Rio de
Janeiro, Brazil. Nine deer showed neurological signs characterized by motor and
proprioceptive deficits. Then neurological signs were mainly depression, incoordination,
dysmetria, ataxia, broad-based members, muscle tremors, loss of tongue tone, frequent falls
and death. Grossly hematomas were observed secondary to trauma caused by dominant males
of the flock, and whitish striations, especially in the renal cortex. Histologic changes included
marked swelling/cytoplasmic vacuolization especially in neurons, progressing to neuronal
lysis and axonal spheroids, in exocrine pancreas, thyroid follicular cells and renal tubular
epithelial cells. In the lectin-histochemical examination the vacuoles were formed by the
accumulation of oligosaccharides specially marked by the lectins WGA, WGA and Con-A.
Ultrastructurally, the swelling/vacuolation corresponded to intense cytoplasmic distention of
lysosomes, formation of residual bodies or dense granular fragments of membranes and
mielinoides bodies. The study has shown the susceptibility of Cervus unicolor to swainsonine
by ingestion of S. carpinifolia. Possibly poisoning the animals in this study was conducted by
food restriction by the hierarchy among males in the group. It might also determine the
marked similarity between clinical and pathological aspects in Sambar deer with the one
presented by other herbivores. / Casos de doen?as induzidas por plantas t?xicas em herb?voros dom?sticos s?o bastante
relatados por todo o mundo e v?m sendo estudados tamb?m no Brasil. Pouco se sabe,
contudo, sobre os aspectos epidemiol?gicos e patol?gicos dessas condi??es em animais
selvagens de vida livre ou criados em cativeiro. Os riscos de desenvolvimento dessas
toxicoses em cativeiros v?m aumentando, conforme os habitats naturais s?o destru?dos pela
a??o humana, e mais centros de conserva??o de vida silvestre e zool?gicos s?o criados. Nesse
estudo s?o descritos os aspectos epidemiol?gicos, biol?gicos e clinicopatol?gicos, lectinohistoqu?micos
e ultraestruturais de um surto de doen?a do armazenamento lisossomal de
oligossacar?deos induzido pela ingest?o de Sida carpinifolia em cervos Sambar jovens
(Cervus unicolor) no zool?gico da Funda??o Rio-Zoo no Estado do Rio de Janeiro. Nove
cervos apresentaram sinais cl?nicos neurol?gicos caracterizados por d?ficits proprioceptivo e
motor. Os sinais neurol?gicos inclu?ram principalmente depress?o, incoordena??o, dismetria,
ataxia, membros em base ampla, tremores musculares, perda do t?nus lingual, quedas
frequentes e morte. Macroscopicamente foram observados hematomas, secund?rios a traumas
provocados por machos dominantes do rebanho, e estria??es esbranqui?adas, principalmente
no c?rtex renal. As les?es histol?gicas inclu?am acentuada tumefa??o/vacuoliza??o
citoplasm?tica especialmente em neur?nios, p?ncreas ex?crino, c?lulas foliculares da tireoides
e do epit?lio renal, necrose neuronal com evolu??o para lise e esferoides axonais. Pelo exame
lectino-histoqu?mico os vac?olos eram formados por ac?mulo de oligossacar?deos marcado
especialmente pelas lectinas S-WGA, WGA e Con-A. Ultraestruturalmente, a
tumefa??o/vacuoliza??o citoplasm?tica correspondeu ? intensa distens?o de lisossomos,
forma??o de corpos residuais densos ou granulares, fragmentos de membranas e corpos
mielinoides. O estudo demonstrou a suscetibilidade de Cervus unicolor ? swainsonina contida
na S. carpinifolia. Possivelmente, a intoxica??o nos animais deste estudo ocorreu pela
restri??o alimentar sofrida pelos animais mais jovens, decorrente da hierarquia entre machos
no grupo. P?de-se determinar ainda a marcada similaridade do quadro cl?nico e patol?gico
entre os cervos descritos nesse trabalho e outros herb?voros dom?sticos.
| Identifer | oai:union.ndltd.org:IBICT/oai:localhost:jspui/2252 |
| Date | 17 August 2010 |
| Creators | Anjos, Bruno Leite dos |
| Contributors | Peixoto, Paulo Fernando de Vargas, Fran?a , Ticiana do Nascimento, Tokarnia, Carlos Hubinger, Dobereiner, Juger, Carvalho, Eul?gio Carlos Queir?z, Varaschin, Mary Susan |
| Publisher | Universidade Federal Rural do Rio de Janeiro, Programa de P?s-Gradua??o em Ci?ncias Veterin?rias, UFRRJ, Brasil, Instituto de Veterin?ria |
| Source Sets | IBICT Brazilian ETDs |
| Language | Portuguese |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/doctoralThesis |
| Format | application/pdf |
| Source | reponame:Biblioteca Digital de Teses e Dissertações da UFRRJ, instname:Universidade Federal Rural do Rio de Janeiro, instacron:UFRRJ |
| Rights | info:eu-repo/semantics/openAccess |
| Relation | ADCOCK, J.L.; KEISS, R. Locoism in elk. Wildlife Disease Association, v.5, p.121? 124, 1969. AGMOULIS, D.P. The pathology of lysosomal storage diseases. Pathology Annual, v.30, p.247-285, 1995. AHERN-RINDELL, A.J.; PRIEUR, D.J.; MURNANE, R.D.; RAGHAVAN, S.S.; DANIEL, P.E.; MCCLEUR, R.H.; WALKLEY, S.U.; PARISH, S.M. Inherited lysosomal storage disease associated with deficiencies of ?-galactosidase and ?- neuraminidase in sheep. American Journal of Medical Genetics, v.31, p.39-56, 1988. ALROY, J.; ORGAD, U.; UCCI, A.A.; GAVRIS, V.E. Swainsonine toxicosis mimics lectin histochemistry of mannosidosis. Veterinary Pathology, v.22, p.311-316, 1985. ANTONIASSI, N.A.B.; FERREIRA, E.V.; SANTOS, C.E.P.; CAMPOS, J.L.E.; NAKAZATO, L.; COLODEL, E.M. Intoxica??o espont?nea por Ipomoea carnea subsp. fistulosa (Convolvulaceae) em bovinos no Pantanal Matogrossense. Pesquisa Veterin?ria Brasileira, v.27, n.10, p.415-418, 2007. ARMI?N, A.G. Vergleichende klinische und morphologische Untersuchungen zur spontanen und experimentellen Vergiftung durch Ipomoea fistulosa (Convolvulaceae) bei Ziegen. Tese de doutorado, Justus-Liebig-Universit?t Giessen, Alemanha, 212p. 2000. ARMI?N, A.G.; TOKARNIA, C.H.; PEIXOTO, P.V.; FRESE, K. Spontaneous and experimental glycoprotein storage disease of goats induced by Ipomoea carnea subsp fistulosa (Convolvulaceae). Veterinary Pathology, v. 44, p.170?184, 2007. ARMI?N, A.G.; TOKARNIA, C.H.; PEIXOTO, P.V.; BARBOSA, J.D.; FRESE, K. Clinical and morphological aspects in sheep and fetuses experimentally poisoned by swainsonine-containing and calystegine-containing plant Ipomoea carnea subsp fistulosa. 2010. Para publica??o. ASSIS, T.S.; MEDEIROS, R.M.T.; RIET-CORREA, F.; GALIZA, G.J.N.; DANTAS, A.F.M.; OLIVEIRA, M.D. Intoxica??o por plantas diagnosticadas em ruminantes e equinos e estimativa das perdas econ?micas na Para?ba. Pesquisa Veterin?ria Brasileira, v.30, n.1, p.13-20, 2010. BALOGH, K.K.I.M.; DIMANDE, A.P, LUGT, J.J.; MOLYNEUX, R.J.; NAUD?, T.W.; WELMAN, W.G. A lysosomal storage disease induced by Ipomoea carnea in goats in Mozambique. Journal of Veterinary Diagnostic Investigation, v.11, p.266- 273, 1999. BARBOSA, R.C.; RIET-CORREA, F.; MEDEIROS, R.M., LIMA, E.F.; BARROS, S.S.; GIMENO, E.J., MOLYNEUX, R.J.; GARDNER, D.R. Intoxication by Ipomoea sericophylla and Ipomoea riedelii in goats in the state of Para?ba, northestern Brazil. Toxicon, v.47, p.371?379, 2006. 63 BARROS, S.S.; RIET-CORREIA, F.; ANDUJAR, M.B. BARROS, C.S.L.; M?NDEZ, M.C.; SCHILD, A.L. Solanum fastigiatum var. fastigiatum and Solanum spp. poisoning in cattle: ultrastructural changes in the cerebellum. Pesquisa Veterin?ria Brasileira, v.7, n.1, p.1-5, 1987. BARROS, C.S.L.; DRIEMEIER, D.; DUTRA, I.S.; LEMOS, R.A.A. Doen?as do Sistema Nervoso de Bovinos no Brasil. Montes Claros, MG: Vall?e, 2006. 207p. BEDIN, M.; COLODEL, E.M.; GIUGLIANI, R.; ZLOTWSKI, P.; CRUZ, C.E.F.; DRIEMEIER, D. Urinary oligosaccharides: a peripheral marker for Sida carpinifolia exposure or poisoning. Toxicon, v.53, p.591?594, 2009. BLAKEMORE, W.F. A case of mannosidosis in the cat: clinical and histopathological findings. Journal of Small Animals Practice, v.27, p. 447-455, 1986. BOURKE, C.A. The clinico-toxicological differentiation of Phalaris spp. Toxicity syndromes in ruminants, p.523-528. In: COLEGATE, S.M., DORLING, P.R. (Ed) Plant-associated toxins. Agricultural, Phytochemical and Ecological Aspects. Slough, UK: CAB International, Farnham Royal, 1994. 596p. BRYAN, L.; SCHMUTZ, S.; HODGES, S.D.; SNIDER, F.F. Bovine B-mannosidosis: pathologic and genetic findings in Salers calves. Veterinary Pathology, v.30, p.130- 139, 1993. BUNDZA, A.; LOWDEN, J.A.; CHARLTON, K.M. Niemann-Pick disease in a poodle dog. Veterinary Pathology, v.16, p.530-538, 1979. CANAVAGH, K.T.; JONES, M.Z.; ABBITT, B.; SKINNER, R. Bovine plasma Bmannosidase activity and its potential use for ?-mannosidosis carrier detection. Journal of Veterinary Diagnostic Investigation, v.4, n.4, p.434-440, 1992. COLODEL, E.M.; DRIEMEIER, D.; LORETTI, A.P.; GIMENO, E.J., TRAVERSO, S.D.; SEITZ, A.; ZLOTOWSKI, P. Aspectos cl?nicos e patol?gicos da intoxica??o por Sida carpinifolia (Malvaceae) em caprinos no Rio Grande do Sul. Pesquisa Veterin?ria Brasileira, v.22, p.51?57, 2002a. COLODEL, E.M.; GARDNER, D.R.; ZLOTOWSKI, P.; DRIEMEIER, D.; Identification of swainsonine as a glycoside inhibitor responsible for Sida carpinifolia poisoning. Veterinary and Human Toxicology, v.44, n.3, p.177?178, 2002b. DAMIR, H.A.; ADAM, S.E.; TARTOUR, G. The effects of Ipomoea carnea on goats and 20 sheep. Veterinary and Human Toxicology, v.29, p.316-319, 1987. DANTAS, A.F.; RIET-CORREA, F.; GARDNER, D.R.; MEDEIROS, R.M.; BARROS, S.S.; ANJOS, B.L.; LUCENA, R.B. Swainsonine induced lysosomal storage disease in goats caused by the ingestion of Turbina cordata in northeastern Brazil. Toxicon, v.49, p.111?116, 2007. 64 DORLING, R.; HUXTABLE, C.R.; COLEGATE, S.M. Inhibition of lisossomal ?- mannosidase by swainsonine, an indolizidine alkaloid isolated from Swainsona cadescens. Biochemical Journal, v.191, p.649-651, 1980. DRIEMEIER, D.; COLODEL, E. M.; GIMENO, E.J.; BARROS, S.S. Lysosomal storage disease caused by Sida carpinifolia in goats. Veterinary Pathology, v.37, p.53? 159, 2000. DUARTE, J.M.B. Artiodactyla-Cervidae (Veado-catingueiro, Veado-campeiro, Cervodo- pantanal). p.641-664. In: CUBAS, Z.S., SILVA, J.C.R., CAT?O-DIAS, J.L. Tratado de Animais Selvagens. S?o Paulo: Roca, 2006. FOWLER, M.E. Plant poisoning in free-living wild animals: a review. Journal of Wildlife Diseases, v.19, n.1, p.34-43, 1983. FREY, R. Ipomoea carnea ssp. fistulosa (Martius ex-Choisy) Austin: Taxonomy, biology and ecology reviewed and inquired. Tropical Ecology, v.36, p.21-48, 1995. FROSCH, M.P.; ANTHONY, D.C.; DEGIROLAMI, U. O sistema nervoso central. p.1411-1486. In: CUMAR, V.; ABBAS, A.K.; FAUSTO, N.; ROBBINS & COTRAN (Ed) Bases patol?gicas das doen?as. 7ed. Rio de Janeiro: Elsevier, 2005. 1592p. FURLAN, F. H.; LUCIOLI, J.; VERONEZI, L.O.; TRAVERSO, S.D.; GAVA, A. Intoxica??o experimental por Sida carpinifolia (Malvaceae) em bovinos. Pesquisa Veterin?ria Brasileira, v.28, p.35?38, 2008. FURLAN, F.H.; LUCIOLI, J.; VERONEZI, L.O.; MEDEIROS, A.L.; BARROS, S.S.; TRAVERSO, S.D.; GAVA, A. Spontaneous lysosomal storage disease caused by Sida carpinifolia (Malvaceae) poisoning in cattle. Veterinary Pathology, v.46, p.343?347, 2009. GAVA, A.; SOUSA, R.S.; DE DEUS, M.S.; PILATI, C.; CRISTANI, J.; MORI, A.; NEVES, D.S. Phalaris angusta (Gramineae) como causa de enfermidade neurol?gica em bovinos no estado de Santa Catarina. Pesquisa Veterin?ria Brasileira, v.19, p.35? 38, 1999. GODOY, G.S., CASTRO NETO, A.; MOMO, C.; DUNE, A.C.C.; ?VILA, L.G.; ALESSI, A.C.; MARQUES, L.C., CASTRO, M.B. Intoxica??o natural por Sida carpinifolia (Malvaceae) em caprinos no estado de S?o Paulo. Arquivo Brasileiro de Medicina Veterin?ria e Zootecnia, v.57(supl.l.), p.25, 2005. GOLDSTEIN, I.J.; HAYES, C.E. The lectins: carbohydratebinding proteins of plant and animals. Advances in Carbohydrate Chemistry & Biochemistry, v.35, p.127?340, 1978. GOLDSTEIN, I.J.; HAYES, C.E.; MONSIGNY, M.; OSAWA, T.; SHARON, N. What should be called a lectin? Nature, v.285, p.66, 1980. GUPTA, RC. (Ed.) Veterinary toxicology-basic and clinical principles. EUA: Elsevier, 2007. 1201p. 65 HAASE, R. Seasonal growth of algod?o-bravo (Ipomoea carnea spp. fistulosa). Pesquisa Agropecu?ria Brasileira, v.34, p.159-163, 1999. HARAGUCHI, M.; GORNIAK, S.L.; IKEDA, K.; MINAMI, Y.; KATO, A. WATSON, A.A.; NASH, R.J.; MOLINEUX, R.J.; AZANO, N. Alkaloidal components in the poisonous plant, Ipomoea carnea (Convolvulaceae). Journal of Agricultural and Food Chemistry, v.51, p.4995-5000, 2003. HARTLEY, W.J.; BLAKEMORE, W.F. Neurovisceral glucocerebroside storage disease (Gaucher?s disease) in a dog. Veterinary Pathology, v.10, p.191-201, 1973a. HARTLEY, W.J.; BLAKEMORE, W.F. Neurovisceral storage and dysmyelogenesis in neonatal goats. Acta Neuropathologica (Berl), v.25, p.325-333, 1973b. HASKINS, M.E.; OTIS, E.J.; HAYDEN, J.E.; JEZYK, P.E.; STRAMM, L. Hepatic storage of glycosaminoglycans in feline and canine models of mucopolysaccharidosis II, VI and VII. Veterinary Pathology, v.29, p.112-119, 1992. HEALY, P.J.; HARPER, P.A.; DENNIS, J.A. Fenotipic variation in bovine ?? mannosidosis. Research in Veterinary Science, v.49, n.1, p.82-84, 1990. HEALY, P.J.; KIDD, G.N.; REUTER, R.E.; BUNCE, C.; HOSIE, I.; STAPLETON T. ?-Mannosidosis in Salers calves in Australia. Australian Veterinary Journal, v.69, p.145, 1991. IKEDA, K.; KATO, A.; ADACHI, I.; HARAGUCHI, M.; ASANO, N. Alkaloids from the poisoning plant Ipomoea carnea: effects on intracellular lysosomal glycosidase activities in human lymphoblast culture. Journal of Agricultural and Food Chemistry, v.51, p.7642?7646, 2003. JAMES, L.F.; PANTER, K.E. Locoweed poisoning in livestock. p.23?38. In: JAMES, L.F.; ELBEIN, A.D.; MOLYNEUX, R.J.; WARREN, C.D. (Eds.), Swainsonine and related glycosidase inhibitors. Iowa State University Press, Ames, 1989. JOLLY, R.D.; BLAKEMORE, W.F. Inherited lysosomal storage disease: an essay in comparative medicine. Veterinary Record, v.92, p.391-400, 1973. JOLLY, R.D.; THOMPSON, K.G. The pathology of bovine mannosidosis. Veterinary Pathology, v.15, p.141-152, 1978. JOLLY, R.D.; SHIMADA, A.; DOPFMER, I.; SLACK, P.M.; BIRTLES, M.J.; PALMER, D.N. Ceroid-lipofuscinosis (Batten?s disease): pathogenesis and sequential neuropathological changes in the ovine model. Neuropathology and Applied Neurobiology, v.15, p.371-383, 1989. JOLLY, R.D., WALKLEY, S.U. Lysosomal storage disease of animals: an essay in comparative pathology. Veterinary Pathology, v.34, p.527?548, 1997. 66 KEANE, D.P.; BARR, D.J.; BOCHSLER, P.N.; HALL, S.M.; GIDLEWSKI, T.; O?ROURKE, K.I.; SPRAKER, T.R.; SAMUEL, M.D. Chronic wasting disease in a Wisconsin white-tailed deer farm. Journal of Veterinary Diagnostic Investigation, v.20, p.698-703, 2008. KELLERMAN, T.S.; COETZER, J.A.W.; NAUD, T.W.; BOTHA, C.J. Plant poisonings and mycotoxicoses of livestock in South Africa. 2ed. EUA: Oxford university press, 2007. 256p. KIILL, L.H.P.; RANGA, N.T. Biologia da reprodu??o de Turbina cordata (Choisy) Austin & Staples (Convolvulaceae) no sert?o Pernambucano, Brasil. Sitientibus s?rie Ci?ncias Biol?gicas, v.4, n.1/2, p.14?19, 2004. KISSMANN, K. G; GROTH, D. Plantas infestantes e nocivas. 2.ed. S?o Paulo: BASF Brasileira, Tomo III, 1997. 683p. KNOWLES, K.; ALROY, J.; CASTAGNARO, M.; RAGHAVAN, S.S.;JAKOWSKI, R.M.; FREDEN, G.O. Adult-onset lysosomal storage disease in a Schipperd dog: clinical, morphological and biochemical studies. Acta Neuropathologica (Berl), v.86, p.306-312, 1993. KOPPANG, N. English Setter model and juvenile ceroidlipofuscinosis. American Journal of Medical Genetics, v.42, p.599-604, 1992. LOCKE, K.B.; MCEWAN, D.R.; HAMDORF, I.J. Experimental poisoning of horses and cattle with Swainsona canascens var horniana. Australian Veterinary Journal, v.56, p.379-383, 1980. LORENZI, H. Plantas Daninhas do Brasil: terrestres, aqu?ticas, parasitas, t?xicas e medicinais. 5ed. Nova Odessa, SP: Plantarum, 2000. p.471-478. LORETTI, A.P.; COLODEL, E.M.; DRIEMEIER, D.; CORREA, A.M.; BANGEL, J.J.J.; FERREIRO, L. Neurological disorder in dairy cattle associated with consumption of beer residues contamined with Aspergillus clavatus. Journal of Veterinary Diagnostic Investigation, v.15, p.123-132, 2003a. LORETTI, A.P.; COLODEL, E.M.; GIMENO, E.J.; DRIEMEIER, D. Lysossomal storage disease in Sida carpinifolia toxicosis: an induced mannosidosis in horses. Equine Veterinary Journal, v.35, p.434-438, 2003b. MAXIE M.G.; YOUSSEF, S. Nervous system. p.283-455. In: MAXIE, M.G. (Ed). Jubb, Kennedy and Palmers ? Pathology of domestic animals. EUA :Saunders, 5ed vol1, 2007. 2340p. MEDWAY, L. The wild mammal of Malaya (Peninsula Malaysia and Singapore). 2ed, Kuala lumpur: Oxford University press, 1983. 131p. NEUFELD, E.F. Lysosomal storage diseases. Annual Review of Biochemistry, v.60, p.257-280, 1991. 67 NOWAK, R. Walker's Mammals of the World, 6th ed. Baltimore and London: The Johns Hopkins University Press. 1999. PAN, Y.T; GHIDONI, J; ELBEIN, A.D. The effects of castanospermine and swainsonine on the activity and synthesis of intestinal sucrase. Archives of Biochemistry Biophysics, v.303, p.134?144, 1993. PANTER, K.E; BUNCH, T.D; JAMES, LF.; SISSON, D.V. Ultrasonographic imaging to monitor fetal and placental developments in ewes fed locoweed (Astragalus lentiginosus). American Journal of Veterinary Research, v.48, p.686-690, 1987. PAULOVICH, F.B.; PORTIANSKY, E.L.; GIMENO, E.J.; SCHILD, A.L.; M?NDEZ, M.D.; RIET-CORREA, F. Lectin histochemical study of lipopigments present in the cerebellum of Solanum fastigiatum var. fastigiatum intoxicated cattle. Journal of Veterinary Medicine Series A - Physiology Pathology Clinical Medic, v.49, p.473- 477, 2002. PAYNE, J.C.; FRANCIS, K.; PHILLIPPS. A Field Guide to the Mammals of Borneo. Malaysia: The Sabah Society with WWF Malaysia, 1985. PEDROSO, P.M.O.C.; VON HOHENDORF, R.; OLIVEIRA, L.G.S.S.; SCHMITZ, M.; CRUZ, C.E.F.; DRIEMEIER, D. Sida carpinifolia (Malvaceae) poisoning in Fallow Deer (Dama dama). Journal of Zoo and Wildlife Medicine, v.40, p.583-585, 2009. PEIXOTO, P.V; TOKARNIA, C.H. Comunica??o pessoal, 2010. PIMENTEL, L.A.; OLIVEIRA, D.M.; GALIZA, G.J.N.; REGO, R.O.; DANTAS, A.F.M.; RIET-CORREA, F. Doen?as do sistema nervoso central de equideos no semi?rido. Pesquisa Veterin?ria Brasileira, v.29, n.7, p.589-597, 2009. PORWAL, M.C.; ROY, P.S.; CHELLAMUTHU, V. Wildlife habitat analysis for 'sambar' (Cervus unicolor) in Kanha National Park using remote sensing. International Journal of Remote Sensing, v.17, n.14, p.2683-2697, 1996. PRITCHARD, H.; NAPTHINE, D.V.; SINCLAIR, A.J. Globoid cell leucodystrophy in polled Dorset sheep. Veterinary pathology, v.17, n.4, p.399-405, 1980. RALPHS, M.H.; JAMES, L.F. Locoweed grazing. Journal of Natural Toxins, v.8, p.47?51, 1999. RECH, R.R.; RISSI, D.R.; RODRIGUES, A.; PIEREZAN, F.; PIAZER, J.V.M.; KOMMERS, G.D.; BARROS, C.S.L. Intoxica??o por Solanum fastigiatum (Solanaceae) em bovinos: epidemiologia, sinais cl?nicos e morfometria das les?es cerebelares. Pesquisa Veterin?ria Brasileira, v.26, p.183-189, 2006. RIET-CORREA, F.; M?NDEZ, M.D.; SCHILD, A.L.; SUMMERS, B.A.; OLIVEIRA, J.A. Intoxication by Solanum fastigiatum var. fastigiatum as a cause of cerebellar degeneration in cattle. Cornell Veterinary, v.73, p.240-256, 1983a. 68 RIET-CORREA, F.; SCHILD, A.L.; M?NDEZ, M.C.; TAVARES, A.S.; RODRIGUES, J.O. Intoxica??o por Claviceps paspali em bovinos no Rio Grande do Sul. Pesquisa Veterin?ria Brasileira, v.3, n.2, p.59-65, 1983b. RIET-CORREA, F.; TABOSA, I.M.; AZEVEDO, E.O.; MEDEIROS, R.M.T.; SIM?ES, S.V.D.; DANTAS, A.F.M.; ALVES, C.J.; NOBRE, V.M.T.; ATHAYDE, A.C.R.; GOMES, A.A.; LIMA E.F. Semi-?rido em Foco, Patos-UFCG, v.1, n.1, p.56- 57, 2003. RIET-CORREA, F.; M?NDEZ, M.C. Intoxica??o espont?nea por plantas e micotoxinas. In: RIET-CORREA, F.; SCHILD, A.L.; LEMOS, R.A.A., BORGES, J.R.J. (Eds.), Doen?as de Ruminantes e Equideos, 3ed. vol 2. Santa Maria, Brazil: Pallotti, 2007. p. 99?221. RIET-CORREA, F.; BARROS, S.S.; M?NDEZ, M.C.; GEVEHR-FERNANDES, C.; NETO, O.A.P.; SOARES, M.P.; MCGAVIN, M.D. Axonal degeneration in sheep caused by the ingestion of Halimium brasiliense. Journal of Veterinary Diagnostic Investigation, v.21, p.478?486, 2009. SCHMITT, S.M.; COOLEY, T.M.; FITZGERALD, S.D.; BOLIN, S.R.; LIM, A.; SCHAEFER, S.M.; KIUPEL, M.; MAES, R.K.; HOGLE, S.A.; O?BRIEN, D.J. An outbreak of eastern equine encephalitis virus in free-ranging white-tailed deer in Michigan. Journal of Wildlife Diseases, v.43, n.4, p.635?644, 2007. SEITZ, A.L.; COLODEL, E.M.; SCHMITZ, M.; GIMENO, E.J.; DRIEMEIER, D. Sida carpinifolia (Malvaceae) poisoning in sheep. The Veterinary Record, v.156, p.386? 388, 2005. SOUSA, S.S.; IRIGOYEN, L.F. Intoxica??o experimental por Phalaris angusta (Gramineae) em bovinos. Pesquisa Veterin?ria Brasileira, v.19, n.3/4, p.116-122, 1999. STEGELMEIER, B.L.; MOLYNEUX, R.J., ELBEIN, A.D.; JAMES, L.F. The lesions of locoweed (Astragalus mollissimus), swainsonine, and castanospermine in rats. Veterinary Pathology, v.32, p.289-298, 1995. STEGELMEIER, B.L.; JAMES, L.F.; PANTER, K.E.; RALPHS, M.H.; GARDNER, D.R.; MOLYNEUX, R.J.; PFISTER, J.A. The pathogenesis and toxicokinetics of locoweed (Astragalus and Oxytropis subsp.) poisoning in livestock. Journal of Natural Toxins, v.8, p.35?45, 1999. STEGELMEIER, B.L.; JAMES, L.F.; PANTER, K.E.; LEE, S.T.; RALPHS, M.H; PFISTER, J.A.; SPRAKER, T.R. Locoweed (Oxytropis sericea)-induced lesions in mule deer (Odocoileius hemionus). Veterinary Pathology, v.42, p.566?578, 2005. STEIN, L.T.; RECH, R.R.; HARRISON, L.; BROWN, C.C. Imunohistochemical study of rabies virus within the central nervous system of domestic and wildlife species. Veterinary Pathology, v.47, n.4, p.630-633, 2010. 69 SUMMERS, B.A.; CUMMINGS, J.F.; LAHUNTA, A. Degenerative diseases of the central nervous system: metabolic and circulatory disorders, p.208-349. In: ___ (Ed.), Veterinary Neuropathology. St Louis, Missouri: Mosby, 1994. 527p. TATE, G. Mammals of Eastern Asia. New York: The Macmillan Company, 1947. TOKARNIA, C.H.; D?BEREINER, J.; CANELLA, C.F.C. Estudos experimental sobre a toxidez do ?canudo?(Ipomoea fistulosa) em ruminantes. Arquivos do Intsituto de Biologia Animal, v.3, p.59-71, 1960. TOKARNIA, C.H.; D?BEREINER, J.; PEIXOTO, P.V. Plantas T?xicas do Brasil. Rio de Janeiro: Helianthus, 2000. 310 p. TULSIANI, D.R.P.; HARRIS, T.M.; TOUSTER, O. Swainsonine inhibits the biosynthesis of complex glycoproteins by inhibition of Golgi mannosidase II. Biological Chemistry, v.257, n.14, p.7936-7939, 1982. VAN DER LUGT, J.J. 2002. Lysosomal storage diseases, p.15-16. In: VAN DER LUGT, J.J. (ed.) The Clinicopathology and Pathology of Selective Toxicoses and Storage Diseases of the Nervous System of Ruminants in Southern Africa. The Netherlands: University of Utrecht. 174p. VANDEVELDE, M.; FRANKHAUSER, R.; BICHSEL, P.; WIESMANN, U.; HERSCHKOWITZ, N. Hereditary neurovisceral mannosidosis associated with ?- mannosidase deficiency in a family of Persian cats. Acta Neuropathologica (Berl), v.58, p. 64-68, 1988. WALVOORT, H.C. Canine glycogen storage disease type II. A biochemical study of an ?-glucosidase-deficient Lapland dog. Biochem Biophys Acta, v.715, p. 63-69, 1982. WELSH, S.L, ATWOOD, N.D.; GOODRICH, S.; HIGGINS, L.C. eds. A Utah Flora.3 ed. Brigham Young University Press, Provo, Utah, 2003. WOLFE, G.J.; LANCE, W.R. Locoweed poisoning in a northern New Mexico elk herd. Journal of Range Manage, v.37, p.59-63, 1984. ZACHARY, J.F. Nervous system. In: MCGAVIN, M.D.; ZACHARY, F. p.833-971. Pathologic basis of veterinary disease, 4ed. Philadelphia, Elsevier: 2007. 1476p. ZAMBRANO, M.S.; RIET-CORREA, R.; SCHILD, A.L.; M?NDEZ, M.C. Intoxica??o por Solanum fastigiatum var. fastigiatum: evolu??o e reversibilidade das les?es em bovinos, e suscetibilidade de ovinos, coelhos, cobaias e ratos. Pesquisa Veterin?ria Brasileira, v.5, n.4, p.133-141, 1985. ZHOU,X.Y.; MORREAU, H.; ROTTIER, R.; DAVIS, D.; BOUTEN, E.; GILLEMANS, N.; WENGER, D.; GROSVELT, F.G.; DOHERTY, P.; SUZUKI, K.; GROSVELT, G.C.; D?AZZO, A. Mouse model for the lysosomal disorder galactosialidosis and correction of the phenotype with over expressing erythroid precursos cells. Genes & Development, v.9, p. 2623-2634, 1995. |
Page generated in 0.0036 seconds