Forty-six constituents have been identified from an ethanol extract prepared from the aerial parts of Desmodium styracifolium, including seven triterpenes: lupeol (15), lupeone (16), olean-12-ene-3beta, 22beta-diol (sophoradiol) (19), olean-12-ene-3beta, 22beta, 24-triol (soyasapogenol B) (20), (23Z)-9, 19-cycloart-23-ene-3beta, 25-diol (21), (24R)-cycloart-25-ene-3beta, 24-diol (24a), and (24S)-cycloart-25-ene-3beta, 24-diol (24b); one triterpene saponin: 3-O-[alpha-rhamnopyranosyl (1→2)-beta-galactopyranosyl (1→2)-beta-glucuronopyranosyl] soyasapogenol B (soyasaponin I) (53); three phytosterols: beta-sitosterol (17), stigmasterol (18), and daucosterol (47); sixteen isoflavanones and O-glycosides: 5, 7-dihydroxy-2', 4'-dimethoxy-isofavanone (homoferreirin) (22), 5, 7, 4'-trihydroxy-2'-methoxy-isofavanone (isoferreirin) (23), (3R)-5, 7-dihydroxy-2', 3', 4'-trimethoxy-isoflavanone (25a), (3S)-5, 7-dihydroxy-2', 3', 4'-trimethoxy-isoflavanone (25b), (3R)-5, 7-dihydroxy-2'-methoxy-3', 4'-methylenedioxy-isoflavanone (26a), (3S)-5, 7-dihydroxy-2'-methoxy-3, 4'-methylenedioxy-isoflavanone (26b), 5, 7, 3'-trihydroxy-2', 4'-dimethoxy-isoflavanone (secundiflorol H) (40), 5, 7, 2', 4'-tetrahydroxy-isoflavanone (dalbergiodin) (41), 3, 5, 7, 4'-tetrahydroxy-2, 2'-epoxyisoflavanone (42), (3R)-5, 7-dihydroxy-2', 3', 4'-trimethoxy-isoflavanone 7-O-beta-glucopyranoside (48a), (3S)-5, 7-dihydroxy-2, 3', 4'-trimethoxy-isoflavanone 7-O-beta-glucopyranoside (48b), (3R)-5, 7-dihydroxy-2'-methoxy-3', 4'-methylenedioxy-isofavanone 7-O-beta-(glucopyranoside (49a). (Abstract shortened by UMI.) / In the present study, two medicinal plants were investigated for their organic constituents. Plant samples were extracted and purified by chromatographic separation using a combination of methods. Each compound isolated was characterized by spectroscopic and physical data. A number of new chemical structures were found. / The investigation has led to the isolation and structural elucidation of fourteen pure compounds from an ethanol extract prepared from the dried rhizomes of Alisa orientale, including three types of skeletons: protostane triterpene, guaiane sesquiterpene and phytosterol. They were identified to be beta-sitosterol (1), (17S)-3, 11-dioxo-23-nor protost-12-en-23 (17)-olide (2), alisol B 23-acetate (3), alismol ( 4), alismoxide (5), alisol B (6), alisol A (7), 25-O-methylalisol A (8), 25-anhydroalisol A 24-acetate (9), 25-anhydroalisol A (10), alisol E 23-acetate (11), daucosterol 6'-stearate (12), (20R, 23S, 24R)-23, 24, 25-trihydroxy-2, 3-seco protost-13 (17)-en-3-oic acid 2, 11beta-lactone (13), and 13beta, 17beta-epoxyalisol A (14). Among them, compound 2 was a new naturally occurring skeleton of 23-nor protostane triterpene, and compound 13 a new 2, 3-seco-protostane triterpene. / Zhao Ming. / "September 2005." / Adviser: Chun-Tao Che. / Source: Dissertation Abstracts International, Volume: 67-07, Section: B, page: 3812. / Thesis (Ph.D.)--Chinese University of Hong Kong, 2005. / Includes bibliographical references (p. 179-187). / Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Electronic reproduction. [Ann Arbor, MI] : ProQuest Information and Learning, [200-] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Abstract in English and Chinese. / School code: 1307.
| Identifer | oai:union.ndltd.org:cuhk.edu.hk/oai:cuhk-dr:cuhk_343680 |
| Date | January 2005 |
| Contributors | Zhao, Ming, Chinese University of Hong Kong Graduate School. Division of Chinese Medicine. |
| Source Sets | The Chinese University of Hong Kong |
| Language | English, Chinese |
| Detected Language | English |
| Type | Text, theses |
| Format | electronic resource, microform, microfiche, 1 online resource (xiii, 259 p. : ill.) |
| Rights | Use of this resource is governed by the terms and conditions of the Creative Commons “Attribution-NonCommercial-NoDerivatives 4.0 International” License (http://creativecommons.org/licenses/by-nc-nd/4.0/) |
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