These studies were conducted to examine the
influence of several variables on the growth hormone binding
protein (GHBP) in serum of pigs. Continuous long term
porcine somatotropin (pST) injections (daily for 6-7 wk)
increased GHBP activity (p < .05). However, periodic short
term pST injections (daily, every second d or every fourth d
for 2 wk) did not cause significant change in GHBP levels (p
> .40). No difference was observed between fed animals and
animals fasted for 5 days (p > .3). Between 0 and 6 mo of
age boar and gilt serum GHBP activity were not significantly
different from each other, but increased significantly with
age in both sexes(p < .0001). There was no significant
correlation between serum GHBP and body weight in this study
(p > .30). In pregnant sows, GHBP concentrations were
highest at the beginning (day 72) of the third trimester (p< .05). These values were compared with information in the
literature on serum growth hormone (GH) concentrations and
GH receptor activity under similar conditions. Growth
hormone receptor activity reported by other researchers and
GHBP activity appear to vary concurrently except during
fasting which may indicate alternate regulation of either
the GHBP or the GH receptor. / Graduation date: 1992
| Identifer | oai:union.ndltd.org:ORGSU/oai:ir.library.oregonstate.edu:1957/37005 |
| Date | 13 September 1991 |
| Creators | Mullins, Tracy M. |
| Contributors | Davis, Steven L. |
| Source Sets | Oregon State University |
| Language | en_US |
| Detected Language | English |
| Type | Thesis/Dissertation |
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