Indiana University-Purdue University Indianapolis (IUPUI) / A study was made to determine if heterogenous dentin, devoid
of its antigenic potential, would stimulate reparative dentino-genesis
in the dental pulp. The teeth of two monkeys were capped
with bovine dentin mixed with methyl cellulose and histologic
analysis was made at 21 and 42 days post-operatively. At the 21-day interval, seven of the 17 teeth capped with the experimental
material were successfully repaired with atubular dentin. The
remaining 10 teeth showed varying degrees of inflammation and
repair. The teeth of the second animal (42 days) were stained for
bacteria as an additional diagnostic tool. A direct correlation
was found between delayed healing and inflammation and presence of
bacteria in the pulp. No bacteria were found in pulps which were
successfully repaired. It was concluded that anorganic bovine
dentin seemed to induce calcific repair of the dental pulp in the
absence of bacteria. Autogenous dentin chips appeared to have the
same effect. The importance of including a bacteriologic stain in
the histologic analysis of pulp capping studies was demonstrated.
| Identifer | oai:union.ndltd.org:IUPUI/oai:scholarworks.iupui.edu:1805/4136 |
| Date | January 1967 |
| Creators | Walshe, Martin J. |
| Contributors | Norman, Richard Daviess, 1927-, Shafer, William G., Gish, Charles W., 1923- |
| Source Sets | Indiana University-Purdue University Indianapolis |
| Language | en_US |
| Detected Language | English |
| Type | Thesis |
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