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DNA Sequence Selective Recognition: Synthesis of Azo- and Diimine Compounds

Polyamide containing groove binding agents have been widely reported We now synthesized netropsin analogs containing azo¡Bimine and diimine functional groups in place of the amide functionality and study their biological activities. Some of these analogs were found to have cytotoxicity in the range of 5 g/mL.

Identiferoai:union.ndltd.org:NSYSU/oai:NSYSU:etd-0801104-001611
Date01 August 2004
CreatorsLiu, Ping-Hao
ContributorsHsiu-Fu Hsu, Chi-Wi Ong, Chien-Chung Cheng
PublisherNSYSU
Source SetsNSYSU Electronic Thesis and Dissertation Archive
LanguageCholon
Detected LanguageEnglish
Typetext
Formatapplication/pdf
Sourcehttp://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0801104-001611
Rightsnot_available, Copyright information available at source archive

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