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Segmentace amyloidních plaků v mozcích transgenních potkanů na základě mikroCT dat / Segmentation of amyloid plaques in brains of trangenic rats based on microCT image data

The presence of amyloid plaques in the hippocampus highlights the incidence of Alzheimer’s disease. Manual segmentation of amyloid plaques is very time consuming and increases the time that can be used to monitor the distribution of amyloid plaques. Distribution carries significant information about disease progression and the impact of potential therapy. The automatic or semi-automatic segmentation method can lead to significant savings in the time which are required when the disease has rapid progression. The description of amyloid plaques and the computed tomography are included in this work. In this diploma thesis are three implemented algorithms, two of them are based on published articles and one’s own methodological solution. The conclusion of the thesis is a quantitative evaluation of the accuracy of implemented segmentation procedures.

Identiferoai:union.ndltd.org:nusl.cz/oai:invenio.nusl.cz:413109
Date January 2020
CreatorsKačníková, Diana
ContributorsKolář, Radim, Chmelík, Jiří
PublisherVysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií
Source SetsCzech ETDs
LanguageSlovak
Detected LanguageEnglish
Typeinfo:eu-repo/semantics/masterThesis
Rightsinfo:eu-repo/semantics/restrictedAccess

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