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Prognostický význam PCA3, fúzního genu TMPRSS2:ERG a dalších markerů u karcinomu prostaty / The prognostic value of PCA3, the fusion gene TMPRSS2:ERG and other markers in prostate cancer

The aim of this thesis was to assess the presence of fusion gene TMPRSS2:ERG and expressions of PCA3, miR23b, miR26 and miR221 in PCa. PSA was measured in peripheral blood and tumor tissue (FFPE samples). The presence of fusion gene TMPRSS2:ERG and expression of PCA3 gene and miRNA in FFPE tumor tissue was analysed by RT real-time PCR. This determination would help to identify patients with high-risk tumors.

Identiferoai:union.ndltd.org:nusl.cz/oai:invenio.nusl.cz:173075
Date January 2014
CreatorsHOLÁ, Hana
Source SetsCzech ETDs
LanguageCzech
Detected LanguageEnglish
Typeinfo:eu-repo/semantics/masterThesis
Rightsinfo:eu-repo/semantics/restrictedAccess

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