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Characterization of an Evolutionarily Old Human Alphoid DNA

A recently isolated human alphoid DNA (in plasmid pHH550) has been sequenced and found to have an exceptionally high degree of similarity to the human alphoid consensus sequence, while its component monomers are unusually heterogeneous in sequence. In contrast to other alphoid DNAs, this DNA is found in all primates tested. Thus this may be an evolutionarily old sequence similar to the one from which other human alphoid DNAs diverged. The pHH550 sequences are found on a number of human chromosomes, including 21 and 22. On chromosome 21 most members of this new sequence group are located distal to other alphoid DNAs.

Identiferoai:union.ndltd.org:ETSU/oai:dc.etsu.edu:etsu-works-14516
Date30 January 1993
CreatorsCarnahan, Susan L., Palamidis-Bourtsos, Eleni, Musich, Phillip R., Doering, Jeffrey L.
PublisherDigital Commons @ East Tennessee State University
Source SetsEast Tennessee State University
Detected LanguageEnglish
Typetext
SourceETSU Faculty Works

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