The immunomodulatory effects of Trichinella spiralis or Trichinella pseudospiralis soluble antigen extracts were examined in an effort to characterize the differences in immune responses seen during these Trichinella infections. The newborn larvae extracts of either parasite exhibited similar potency for stimulating macrophage PGE production; however, the muscle larvae extracts of T. pseudospiralis stimulated greater levels of PGE than did the muscle larvae extracts of T. spiralis. These data clearly indicate that Trichinella antigens possess immunomodulatory capabilities.
| Identifer | oai:union.ndltd.org:unt.edu/info:ark/67531/metadc332503 |
| Date | 08 1900 |
| Creators | Dixon, Guy Cameron, 1960- |
| Contributors | Goven, Arthur James, 1950-, Benjamin, Robert C., Kunz, Daniel A., Wu, Edward Ming-chi, 1938- |
| Publisher | University of North Texas |
| Source Sets | University of North Texas |
| Language | English |
| Detected Language | English |
| Type | Thesis or Dissertation |
| Format | viii, 108 leaves : ill., Text |
| Rights | Public, Dixon, Guy Cameron, 1960-, Copyright, Copyright is held by the author, unless otherwise noted. All rights reserved. |
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