PURPOSE: Previous studies have reported an increased prevalence of ocular diseases in patients with obstructive sleep apnea. The purpose of this study was to examine the link between such ocular diseases as diabetic retinopathy, diabetic macular edema, retinal vein occlusion, central serous chorioretinopathy, age-related macular degeneration, non-arteritic anterior ischemic optic neuropathy, and glaucoma.
METHODS: This meta-analysis was conducted through a search using PubMed, Web of Science, Scopus and EMBASE. We identified both retrospective and prospective studies.
RESULTS: The final meta-analysis looked at 30 studies and 7 ocular diseases. The data showed a high prevalence of obstructive sleep apnea for diabetic retinopathy and diabetic macular edema patients. Data for glaucoma and non-arteritic anterior ischemic optic neuropathy patients did not show a statistical increase. There was not enough data for retinal vein occlusion, central serous chorioretinopathy and age-related macular degeneration to calculate statistical significance.
CONCLUSION: These data suggests that patient populations with diabetic retinopathy and macular edema show increased rates of obstructive sleep apnea. Data suggest that hypoxia is an important part of the pathophysiology of diabetic retinopathy and diabetic macular edema. Because obstructive sleep apnea has been shown to affect the progression of the ocular diseases included in this study, ophthalmologists should screen for the presence of obstructive sleep apnea to better help their patients. / 2021-06-14T00:00:00Z
| Identifer | oai:union.ndltd.org:bu.edu/oai:open.bu.edu:2144/36642 |
| Date | 14 June 2019 |
| Creators | Dingillo, Gianna |
| Contributors | Layne, Matthew, Arroyo, Jorge |
| Source Sets | Boston University |
| Language | en_US |
| Detected Language | English |
| Type | Thesis/Dissertation |
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