Re-evaluating cyclosporine A as a hair growth-promoting agent in human scalp hair follicles

Description

No / Cyclosporine A (CsA) has long been recognized as a potent hair growth stimulator in both humans and rodent. The induction of a dose-dependent hypertrichosis is one of the most frequent adverse effects of long-term CsA therapy (Lutz, 1994). However, it is unclear how this immunosuppressant induces hypertrichosis in patients or stimulates hair growth in human scalp skin transplanted on nude mice (Gilhar et al., 1988; Gilhar et al., 1991).

Links & Downloads

1. Hawkshaw NJ, Haslam IS, Ansell DM, Shamalak A and Paus R (2015) Re-evaluating cyclosporine A as a hair growth-promoting agent in human scalp hair follicles. Letter to the Editor. Journal of Investigative Dermatology. 135(8): 2129-2132
2. http://hdl.handle.net/10454/17817
3. https://doi.org/10.1038/jid.2015.121

Tags

Cyclosporine A

Hair growth stimulant

Human scalp

Hair follicles

Additional Fields

Identifer	oai:union.ndltd.org:BRADFORD/oai:bradscholars.brad.ac.uk:10454/17817
Date	07 May 2020
Creators	Hawkshaw, N.J., Haslam, I.S., Ansell, David, Shamalak, A., Paus, R.
Source Sets	Bradford Scholars
Language	English
Detected Language	English
Type	Letter, No full-text in the repository