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The Effect of Mutations in Stearoyl CoA Desaturase Gene and Fatty Acid Synthase on Milk Composition and Fatty Acid Profile in Milk Fat of Dairy Cows

The effects of diet on milk fatty acid profile, including conjugated linoleic acid (CLA) have been well documented, however, there is limited information on the interaction of diet with genetics. The objective of this research was to determine the effect of single nucleotide polymorphisms (SNP) in the stearoyl CoA desaturase (SCD) gene on the ability to produce CLA in dairy cows fed low and high fat diets. The secondary objective was to determine the effect of a SNP in fatty acid synthase (FASN) on milk yield and composition. There was no effect of SCD genotype on CLA concentration, however there was an effect of SCD genotype on the ratio of C14:1/C14:0 which tended to be associated with CLA concentration when animals were fed a high fat diet. The FASN genotype affected milk yield, while composition remained constant. / Animal Science

Identiferoai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:AEU.10048/724
Date11 1900
CreatorsClark, Laura Ashley
ContributorsOba, Masahito (Agricultural, Food, and Nutritional Sciences), Moore, Stephen (Agricultural, Food, and Nutritional Sciences), Dixon, Walter (Agricultural, Food, and Nutritional Sciences), Coltman, David (Biological Sciences)
Source SetsLibrary and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada
LanguageEnglish
Detected LanguageEnglish
TypeThesis
Format464949 bytes, application/pdf

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