Hypertension is a chronic medical condition, and a primary contributor to severe cardiovascular disease. It can increase mortality risk. Studies have found that a low-grade inflammation is involved in the development of hypertension. In addition, men have been found to have a higher risk of hypertension than age-matched women, while women have an increased risk of hypertension after menopause. Female sex hormones are considered to play a protective role in the development and progression of hypertension. Prostanoids are inflammatory mediators, and have important physiological roles on promoting or suppressing inflammation. Studying the combined roles of these two biochemical families in disease development will be helpful to understand the balance between a self-protective effect and inflammatory response in hypertension, and find effective biomarkers to predict the progression of hypertension. In my study, a reversed phase high performance liquid chromatography is used to develop the / Chemistry
| Identifer | oai:union.ndltd.org:TEMPLE/oai:scholarshare.temple.edu:20.500.12613/4025 |
| Date | January 2015 |
| Creators | Wei, Guoxiu |
| Contributors | Varnum, Susan A., Varnum, Susan A., Wunder, Stephanie L., Zdilla, Michael J., 1978-, Shi, Justin Y. |
| Publisher | Temple University. Libraries |
| Source Sets | Temple University |
| Language | English |
| Detected Language | English |
| Type | Thesis/Dissertation, Text |
| Format | 177 pages |
| Rights | IN COPYRIGHT- This Rights Statement can be used for an Item that is in copyright. Using this statement implies that the organization making this Item available has determined that the Item is in copyright and either is the rights-holder, has obtained permission from the rights-holder(s) to make their Work(s) available, or makes the Item available under an exception or limitation to copyright (including Fair Use) that entitles it to make the Item available., http://rightsstatements.org/vocab/InC/1.0/ |
| Relation | http://dx.doi.org/10.34944/dspace/4007, Theses and Dissertations |
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